Evidence map›Paper›PMID 29255717›Full record

ArticleERJ open research2017

HIV-associated disruption of lung cytokine networks is incompletely restored in asymptomatic HIV-infected Malawian adults on antiretroviral therapy.

Kondwani C Jambo, Dumizulu L Tembo, Arox W Kamng'ona, Patrick Musicha, Dominic H Banda, Anstead M Kankwatira, Rose D Malamba, Theresa J Allain, Robert S Heyderman, David G Russell and 1 more

Abstract read
In one paragraph

Article in ERJ open research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kondwani C JamboMalawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi.
Dumizulu L TemboDept of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
Arox W Kamng'onaMalawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi.
Patrick MusichaMalawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi.
Dominic H BandaMalawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi.
Anstead M KankwatiraMalawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi.
Rose D MalambaMalawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi.
Theresa J AllainDept of Medicine, University of Malawi, College of Medicine, Blantyre, Malawi.
Robert S HeydermanMalawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi.
David G RussellDept of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
Henry C MwandumbaMalawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi.

Funding

How does HIV lead to increased susceptibility to tuberculosis?R01AI118582 · NIAID · CORNELL UNIVERSITY · PI RUSSELL, DAVID G · 2015 to 2019
$2.8M
Restoration of alveolar macrophage function in HIV patients: A clinical study.R01HL100928 · NHLBI · CORNELL UNIVERSITY · PI RUSSELL, DAVID G · 2010 to 2014
$2.4M
Are HIV-1-Infected Alveolar Macrophages Productive Sites of Viral Persistence?R21AI136097 · NIAID · CORNELL UNIVERSITY · PI RUSSELL, DAVID G · 2018 to 2019
$426k
Medical Research Council MR/P020526/1NHLBI NIH HHS R01 HL100928NIAID NIH HHS R01 AI118582NIAID NIH HHS R21 AI136097Wellcome Trust
6 · The paper itself

Abstract

Disruption of lung cytokine networks during chronic HIV infection is incompletely restored in individuals on antiretroviral therapy.

Identifiers

PMID29255717
PMCPMC5731235

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.