Evidence map›Paper›PMID 29255623›Full record

ReviewFuture science OA2018

The role of biomarkers in the diagnosis and risk stratification of acute coronary syndrome.

Sanoj Chacko, Sohaib Haseeb, Benedict M Glover, David Wallbridge, Alan Harper

Abstract readReview
In one paragraph

Review in Future science OA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  9. Biomarkers Utility: At the Borderline between Cardiology and Neurology.Journal of cardiovascular development and disease · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sanoj ChackoKeeleCardiovascular Medicine, Keele University, Keele, Staffordshire, ST5 BG, UK.
Sohaib HaseebHeart Rhythm Service, Kingston General Hospital, Queen's University, Kingston, ON, Canada.
Benedict M GloverHeart Rhythm Service, Kingston General Hospital, Queen's University, Kingston, ON, Canada.
David WallbridgeKeeleCardiovascular Medicine, Keele University, Keele, Staffordshire, ST5 BG, UK.
Alan HarperKeeleCardiovascular Medicine, Keele University, Keele, Staffordshire, ST5 BG, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronary artery disease is a growing concern. Although traditional biomarkers, such as troponins and creatine kinase, play a central role in the diagnosis, risk stratification and management of coronary artery disease, they are unable to detect myocardial ischemia in the absence of necrosis. Therefore, early detection of ischemia in patients presenting with acute coronary syndrome still remains a burning question. High-sensitivity troponin is evolving as a reliable biomarker in this regard and has been absorbed into clinical practice. Biomarkers are currently the focus of immense interest as it not only helps with diagnosis and management but also helps to understand the pathophysiology of the disease process. In addition, analysis using a multimarker strategy has also proven to be a very useful tool in risk stratification. This review will focus on the biomarkers and its application in the diagnosis and risk stratification of acute coronary syndrome.

Indexed as

acute coronary syndromebiomarkerscreatine kinaseheart-type fatty acid-binding proteinmyeloperoxidasetroponin

Identifiers

PMID29255623
PMCPMC5729601

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.