Evidence map›Paper›PMID 29255495›Full record

ReviewGenes & nutrition2017

A scheme for a flexible classification of dietary and health biomarkers.

Qian Gao, Giulia Praticò, Augustin Scalbert, Guy Vergères, Marjukka Kolehmainen, Claudine Manach, Lorraine Brennan, Lydia A Afman, David S Wishart, Cristina Andres-Lacueva and 4 more

Abstract readReview
In one paragraph

Review in Genes & nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Qian GaoDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.
Giulia PraticòDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.
Augustin ScalbertBiomarkers Group, Nutrition and Metabolism Section, International Agency for Research on Cancer (IARC), Lyon, France.
Guy VergèresAgroscope, Federal Office of Agriculture, Berne, Switzerland.
Marjukka KolehmainenUniversity of Eastern Finland, Kuopio, Finland.
Claudine ManachINRA, Human Nutrition Unit, Université Clermont Auvergne, INRA, F63000 Clermont-Ferrand, France.
Lorraine BrennanUCD Institute of Food & Health, UCD School of Agriculture and Food Science, University College Dublin, Dublin, Ireland.
Lydia A AfmanDivision of Human Nutrition, Wageningen University & Research, Wageningen, The Netherlands.
David S WishartDepartment of Biological Sciences, University of Alberta, Edmonton, Canada.
Cristina Andres-LacuevaBiomarkers and Nutrimetabolomic Laboratory, Department of Nutrition, Food Sciences and Gastronomy, University of Barcelona, Barcelona, Spain.
Mar Garcia-AloyBiomarkers and Nutrimetabolomic Laboratory, Department of Nutrition, Food Sciences and Gastronomy, University of Barcelona, Barcelona, Spain.
Hans VerhagenEuropean Food Safety Authority (EFSA), Parma, Italy.
Edith J M FeskensDivision of Human Nutrition, Wageningen University & Research, Wageningen, The Netherlands.
Lars O DragstedDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.

Funding

European Research Council 647783World Health Organization 001
6 · The paper itself

Abstract

Biomarkers are an efficient means to examine intakes or exposures and their biological effects and to assess system susceptibility. Aided by novel profiling technologies, the biomarker research field is undergoing rapid development and new putative biomarkers are continuously emerging in the scientific literature. However, the existing concepts for classification of biomarkers in the dietary and health area may be ambiguous, leading to uncertainty about their application. In order to better understand the potential of biomarkers and to communicate their use and application, it is imperative to have a solid scheme for biomarker classification that will provide a well-defined ontology for the field. In this manuscript, we provide an improved scheme for biomarker classification based on their intended use rather than the technology or outcomes (six subclasses are suggested: food compound intake biomarkers (FCIBs), food or food component intake biomarkers (FIBs), dietary pattern biomarkers (DPBs), food compound status biomarkers (FCSBs), effect biomarkers, physiological or health state biomarkers). The application of this scheme is described in detail for the dietary and health area and is compared with previous biomarker classification for this field of research.

Indexed as

BiomarkerClassificationEffectExposureMetabolomicsNutritionOntologyReviewSusceptibility

Identifiers

PMID29255495
PMCPMC5728065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.