ArticleFrontiers in endocrinology2017
The Stem Cell Connection of Pituitary Tumors.
Article in Frontiers in endocrinology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 20 citations in OpenAlex.
- Analysis of senescence in pituitary tumors from different lineages and the potential role of senolytic drugs as targeted therapies.Frontiers in endocrinology · 2026Article
- Pituitary tumours without distinct lineage differentiation express stem cell marker SOX2.Pituitary · 2024Article
- Drug Repositioning for Refractory Benign Tumors of the Central Nervous System.International journal of molecular sciences · 2023Review
- Single-cell sequencing identifies differentiation-related markers for molecular classification and recurrence prediction of PitNET.Cell reports. Medicine · 2023Article
- Transcriptome of GH-producing pituitary neuroendocrine tumours and models are significantly affected by somatostatin analogues.Cancer cell international · 2023Article
- Organoid models of the pituitary gland in health and disease.Frontiers in endocrinology · 2023Review
- Pathogenesis, clinical features, and treatment of plurihormonal pituitary adenoma.Frontiers in neuroscience · 2023Review
- Article
- Architects of Pituitary Tumour Growth.Frontiers in endocrinology · 2022Review
- Up-regulation of sex-determining region Y-box 9 (SOX9) in growth hormone-secreting pituitary adenomas.BMC endocrine disorders · 2021Article
- Editorial: Stem Cells in Endocrine Tumors.Frontiers in endocrinology · 2021Article
- Article
- Pituitary Remodeling Throughout Life: Are Resident Stem Cells Involved?Frontiers in endocrinology · 2020Review
- Experimental Evidence and Clinical Implications of Pituitary Adenoma Stem Cells.Frontiers in endocrinology · 2020Review
- Molecular alterations in non-functioning pituitary adenomas.Cancer biomarkers : section A of Disease markers · 2020Article
- Stem Cells in Pituitary Tumors: Experimental Evidence Supporting Their Existence and Their Role in Tumor Clinical Behavior.Frontiers in endocrinology · 2019Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tumors in the pituitary gland are typically benign but cause serious morbidity due to compression of neighboring structures and hormonal disruptions. Overall, therapy efficiency remains suboptimal with negative impact on health and comfort of life, including considerable risk of therapy resistance and tumor recurrence. To date, little is known on the pathogenesis of pituitary tumors. Stem cells may represent important forces in this process. The pituitary tumors may contain a driving tumor stem cell population while the resident tissue stem cells may be directly or indirectly linked to tumor development and growth. Here, we will briefly summarize recent studies that afforded a glance behind the scenes of this stem cell connection. A better knowledge of the mechanisms underlying pituitary tumorigenesis is essential to identify more efficacious treatment modalities and improve clinical management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.