Evidence map›Paper›PMID 29255407›Full record

ReviewFrontiers in systems neuroscience2017

PACAP/Receptor System in Urinary Bladder Dysfunction and Pelvic Pain Following Urinary Bladder Inflammation or Stress.

Beatrice M Girard, Katharine Tooke, Margaret A Vizzard

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in systems neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. PACAP/PAC1 Expression and Function in Micturition Pathways.Journal of molecular neuroscience : MN · 2019
    Review
  8. Article
  9. PACAP38 and PACThe journal of headache and pain · 2018
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Beatrice M GirardDepartment of Neurological Sciences, Larner College of Medicine, The University of Vermont, Burlington, VT, United States.
Katharine TookeDepartment of Neurological Sciences, Larner College of Medicine, The University of Vermont, Burlington, VT, United States.
Margaret A VizzardDepartment of Neurological Sciences, Larner College of Medicine, The University of Vermont, Burlington, VT, United States.
University of Vermont · US

Funding

UCD Mutant Mouse Regional Resource CenterU42OD012210 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KC KENT LLOYD · 2012 to 2026
$29.2M
Cystitis-Induced Plasticity of Micturition ReflexesR01DK051369 · NIDDK · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI VIZZARD, MARGARET ANN · 2003 to 2017
$5.4M
Developmental Plasticity of Micturition ReflexesR01DK060481 · NIDDK · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI VIZZARD, MARGARET ANN · 2002 to 2018
$4.5M
Center for Neuroscience ExcellenceP30GM103498 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI PARSONS, RODNEY L · 2012 to 2015
$4.3M
CENTER FOR NEUROSCIENCE EXCELLENCEP30RR032135 · NCRR · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI PARSONS, RODNEY L · 2011 to 2011
$1.1M
Developmental plasticity of micturation reflexesR56DK060481 · NIDDK · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI VIZZARD, MARGARET ANN · 2008 to 2008
$232k
IRRITATION INDUCED PLASTICITY OF MICTURITION PATHWAYSR29DK051369 · NIDDK · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI VIZZARD, MARGARET ANN · 1996 to 2000
$109k
NCRR NIH HHS P30 RR032135NIDDK NIH HHS R01 DK051369NIDDK NIH HHS R01 DK060481NIDDK NIH HHS R29 DK051369NIDDK NIH HHS R56 DK060481NIGMS NIH HHS P30 GM103498NIH HHS U42 OD012210
6 · The paper itself

Abstract

Complex organization of CNS and PNS pathways is necessary for the coordinated and reciprocal functions of the urinary bladder, urethra and urethral sphincters. Injury, inflammation, psychogenic stress or diseases that affect these nerve pathways and target organs can produce lower urinary tract (LUT) dysfunction. Numerous neuropeptide/receptor systems are expressed in the neural pathways of the LUT and non-neural components of the LUT (e.g., urothelium) also express peptides. One such neuropeptide receptor system, pituitary adenylate cyclase-activating polypeptide (PACAP;

Indexed as

cyclophosphamideinflammationmicturitionneuropeptidesNGFPAC1PACAP(6-38)psychogenic stress

Identifiers

PMID29255407
PMCPMC5722809
OpenAlexW2772666645

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.