ArticleScientific reports2017
The kinematics of handwriting movements as expression of cognitive and sensorimotor impairments in people with multiple sclerosis.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 23 citations in OpenAlex.
- Neural and motor mechanisms of handwriting: from healthy aging to neurodegenerative disorders.Frontiers in aging neuroscience · 2026Review
- Effects of exercise-cognitive dual-task training on cognitive frailty in older adults: a randomized controlled trial.Frontiers in aging neuroscience · 2025Article
- Preliminary validity of the Draw a Shape Test for upper extremity assessment in multiple sclerosis.Annals of clinical and translational neurology · 2023Article
- Reaching to inhibit a prepotent response: A wearable 3-axis accelerometer kinematic analysis.PloS one · 2021Article
- Right Inferior Parietal Lobule Activity Is Associated With Handwriting Spontaneous Tempo.Frontiers in neuroscience · 2021Article
- Smoothness: an Unexplored Window into Coordinated Running Proficiency.Sports medicine - open · 2019Article
- Handwriting movements for assessment of motor symptoms in schizophrenia spectrum disorders and bipolar disorder.PloS one · 2019Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Handwriting is an important activity of daily living, which requires sensorimotor and cognitive skills that could deteriorate in presence of neurological diseases. Handwriting impairments are common in people with multiple sclerosis (PwMS). Aims of the present study were to characterize handwriting movement features of PwMS in comparison with those of healthy adults, and to evaluate the relationship between kinematic parameters of handwriting movements and the results of the assessment of cognitive and motor domains. A new handwriting evaluation methodology was applied to quantify handwriting features of 19 PwMS and 22 age-matched healthy controls who were required to write a sentence on a digitizing tablet. Kinematic parameters of the sentence and of the strokes were used to evaluate handwriting performance. PwMS showed an altered handwriting kinematics with respect to healthy controls: higher movement duration, fragmented velocity profile and higher jerk. Furthermore, motor abilities and cognitive status of PwMS were related to handwriting parameters in accordance with the evidence that MS is a multifactorial disease affecting different domains. These results suggested that the proposed methodology might be a valuable tool to quantitatively assess handwriting impairments and the efficacy of handwriting treatments in PwMS.
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Registered trials
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