Evidence map›Paper›PMID 29255174›Full record

ArticleScientific reports2017

A Drosophila ex vivo model of olfactory appetitive learning.

Ema Suzuki-Sawano, Kohei Ueno, Shintaro Naganos, Yoshihiro Sawano, Junjiro Horiuchi, Minoru Saitoe

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Pairing-Dependent Plasticity in a Dissected Fly Brain Is Input-Specific and Requires Synaptic CaMKII Enrichment and Nighttime Sleep.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ema Suzuki-SawanoLearning and Memory Project, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa Setagaya, Tokyo, 156-8506, Japan.
Kohei UenoLearning and Memory Project, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa Setagaya, Tokyo, 156-8506, Japan.
Shintaro NaganosLearning and Memory Project, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa Setagaya, Tokyo, 156-8506, Japan.
Yoshihiro SawanoDepartment of Mathematics and Information Science, Tokyo Metropolitan University, 1-1 Minami Ohsawa, Hachioji, Tokyo, 192-0397, Japan.
Junjiro HoriuchiLearning and Memory Project, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa Setagaya, Tokyo, 156-8506, Japan.
Minoru SaitoeLearning and Memory Project, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa Setagaya, Tokyo, 156-8506, Japan. saito-mn@igakuken.or.jp.ORCID 0000-0001-9731-4214

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During olfactory appetitive learning, animals associate an odor, or conditioned stimulus (CS), with an unconditioned stimulus (US), often a sugar reward. This association induces feeding behavior, a conditioned response (CR), upon subsequent exposure to the CS. In this study, we developed a model of this behavior in isolated Drosophila brains. Artificial activation of neurons expressing the Gr5a sugar-responsive gustatory receptor (Gr5a GRNs) induces feeding behavior in starved flies. Consistent with this, we find that in dissected brains, activation of Gr5a GRNs induces Ca

Indexed as

AnimalsAppetitive BehaviorConditioning, ClassicalDrosophilaDrosophila ProteinsFeeding BehaviorNeuronsOdorantsOlfactory CortexOlfactory PathwaysReceptors, Cell SurfaceRewardSmellTasteDrosophila Proteinsgustatory receptor, DrosophilaReceptors, Cell Surface

Identifiers

PMID29255174
PMCPMC5735177

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.