Evidence map›Paper›PMID 29255168›Full record

ArticleBone marrow transplantation2018

Plerixafor in poor mobilizers with non-Hodgkin's lymphoma: a multi-center time-motion analysis.

Mohamad Mohty, Nabih Azar, Christian Chabannon, Steven Le Gouill, Lionel Karlin, Lucia Farina, Gary Milkovich, Helmut Ostermann, Bertram Glaß, Richard Noppeney and 3 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Bone marrow transplantation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
  2. Trial
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  4. Article
  5. Article
  6. Mobilization and Hematopoietic Stem Cell Collection in Poor Mobilizing Patients with Lymphoma: Final Results of the German OPTIMOB Study.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2023
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Observational
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  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mohamad MohtyDepartment of Haematology, Saint-Antoine Hospital, Paris, France. mohamad.mohty@inserm.fr.
Nabih AzarDepartment of Haematology, Pitie-Salpetriere Hospital, Paris, France.
Christian ChabannonCBT-1409: INSERM, Aix Marseille Univ, Institut Paoli-Calmettes, Marseille, France.ORCID http://orcid.org/0000-0002-3755-4889
Steven Le GouillService d'Hématologie, Centre Hospitalo-Universitaire Nantes, Nantes, France.
Lionel KarlinCentre Hospitalier Lyon-Sud, Pierre-Bénite, France.
Lucia FarinaHematology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.
Gary MilkovichRJM Group, LLC, 13028 Smoketown Road, Woodbridge, VA, 22192, USA.
Helmut OstermannDepartment of Internal Medicine III, University of Munich, Munich, Germany.
Bertram GlaßDepartment of Hematology, Oncology and Cancer Immunology, Berlin, Germany.
Richard NoppeneyHematology, University Hospital Essen, Essen, Germany.
Florian KronDepartment I of Internal Medicine, Center for Integrated Oncology, University Hospital of Cologne, Cologne, Germany.
Anna KronDepartment I of Internal Medicine, Center for Integrated Oncology, University Hospital of Cologne, Cologne, Germany.
Kai HübelDepartment of Internal Medicine, University Hospital of Cologne, Cologne, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-dose chemotherapy alongside peripheral blood stem cell (PBSC) infusion has become the standard of care in different hematologic malignancies. The goal of PBSC mobilization is to allow collection of sufficient CD34+ cells to proceed to transplantation. The current mobilization regimen with granulocyte colony-stimulating factor (G-CSF), alone or in combination with chemotherapy, still fails in 10-25% of patients. Plerixafor is able to rescue most of these patients from mobilization failure. In this study, we investigated the impact of plerixafor on the cost and time spent on apheresis in patients who were considered poor mobilizers, with <20 × 10

Indexed as

AdultAgedAntigens, CD34BenzylaminesBlood Component RemovalCyclamsFemaleGranulocyte Colony-Stimulating FactorHematopoietic Stem Cell MobilizationHeterocyclic CompoundsHumansLymphoma, Non-HodgkinMaleMiddle AgedSalvage TherapyTime FactorsAntigens, CD34BenzylaminesCyclamsGranulocyte Colony-Stimulating FactorHeterocyclic Compoundsplerixafor

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.