Evidence map›Paper›PMID 29255078›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

ATP Evokes Ca

Janice A Layhadi, Jeremy Turner, David Crossman, Samuel J Fountain

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 74 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Crosstalk between purinergic receptor P2YCellular and molecular life sciences : CMLS · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Physiologic roles of P2 receptors in leukocytes.Journal of leukocyte biology · 2022
    Review
  11. Article
  12. Article
  13. Review
  14. P2XScientific reports · 2022
    Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Janice A LayhadiSchool of Biological Sciences, University of East Anglia, Norwich, Norfolk NR4 7TJ, United Kingdom.
Jeremy TurnerElsie Bertram Diabetes Centre, Norfolk and Norwich University Hospital, Norwich NR4 7UY, United Kingdom; and.
David CrossmanSchool of Medicine, University of St Andrews, St Andrews KY16 9TF, United Kingdom.
Samuel J FountainSchool of Biological Sciences, University of East Anglia, Norwich, Norfolk NR4 7TJ, United Kingdom; s.j.fountain@uea.ac.uk.ORCID 0000-0002-6028-0548
University of East Anglia · GBAndrews University · USNorfolk and Norwich University Hospital · GB

Funding

Biotechnology and Biological Sciences Research Council BB/F023588/1
6 · The paper itself

Abstract

Leukocytes sense extracellular ATP, a danger-associated molecular pattern, released during cellular stress and death, via activation of cell surface P2X and P2Y receptors. Here, we investigate P2 receptor expression in primary human monocyte-derived macrophages and receptors that mediate ATP-evoked intracellular [Ca

Indexed as

Adenosine TriphosphateCalciumCalcium SignalingCells, CulturedChemokine CXCL5Enzyme ActivationGene Expression RegulationHumansMacrophagesPurinergic P2X Receptor AntagonistsReceptors, Purinergic P2X4Receptors, Purinergic P2YAdenosine TriphosphateCalciumChemokine CXCL5CXCL5 protein, humanPurinergic P2X Receptor AntagonistsReceptors, Purinergic P2X4Receptors, Purinergic P2Y

Identifiers

PMID29255078
PMCPMC5784824
OpenAlexW2780208148

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.