Evidence map›Paper›PMID 29255033›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Remote electrochemical modulation of pK

Giulio Ragazzon, Christian Schäfer, Paola Franchi, Serena Silvi, Benoit Colasson, Marco Lucarini, Alberto Credi

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 38 citations in OpenAlex.

  1. Precision Switching and Coupled Motion in a [3]Rotaxane Molecular Machine.Angewandte Chemie (International ed. in English) · 2026
    Article
  2. Article
  3. Review
  4. Compact Rotaxane Superbases.Journal of the American Chemical Society · 2023
    Article
  5. Article
  6. Anion-π Catalysis Enabled by the Mechanical Bond.Angewandte Chemie (International ed. in English) · 2022
    Article
  7. Review
  8. Direct synthetic routes to functionalised crown ethers.Organic chemistry frontiers : an international journal of organic chemistry · 2021
    Review
  9. Chemically Induced Mismatch of Rings and Stations in [3]Rotaxanes.Journal of the American Chemical Society · 2021
    Article
  10. Article
  11. Precision Molecular Threading/Dethreading.Angewandte Chemie (International ed. in English) · 2020
    Article
  12. Article
  13. Growing community of artificial molecular machinists.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Giulio RagazzonDipartimento di Chimica "G. Ciamician," Università di Bologna, 40126 Bologna, Italy.
Christian SchäferDipartimento di Chimica "G. Ciamician," Università di Bologna, 40126 Bologna, Italy.
Paola FranchiDipartimento di Chimica "G. Ciamician," Università di Bologna, 40126 Bologna, Italy.
Serena SilviDipartimento di Chimica "G. Ciamician," Università di Bologna, 40126 Bologna, Italy.
Benoit ColassonDipartimento di Chimica "G. Ciamician," Università di Bologna, 40126 Bologna, Italy.
Marco LucariniDipartimento di Chimica "G. Ciamician," Università di Bologna, 40126 Bologna, Italy; marco.lucarini@unibo.it alberto.credi@unibo.it.
Alberto CrediDipartimento di Scienze e Tecnologie Agro-alimentari, Università di Bologna, 40127 Bologna, Italy; marco.lucarini@unibo.it alberto.credi@unibo.it.ORCID 0000-0003-2546-9801
University of Bologna · ITCentre National de la Recherche Scientifique · FRInstitute of Organic Synthesis and Photoreactivity · IT

Funding

European Research Council 692981
6 · The paper itself

Abstract

Allosteric control, one of Nature's most effective ways to regulate functions in biomolecular machinery, involves the transfer of information between distant sites. The mechanistic details of such a transfer are still an object of intensive investigation and debate, and the idea that intramolecular communication could be enabled by dynamic processes is gaining attention as a complement to traditional explanations. Mechanically interlocked molecules, owing to the particular kind of connection between their components and the resulting dynamic behavior, are attractive systems to investigate allosteric mechanisms and exploit them to develop functionalities with artificial species. We show that the pK

Indexed as

Models, ChemicalMolecular ConformationBinding SitesElectric StimulationElectrochemical TechniquesElectron TransportEnergy TransferMolecular StructureProtonsRotaxanesProtonsRotaxanesacid–base processeselectrochemistryfree energy changemolecular machinemolecular switch

Identifiers

PMID29255033
PMCPMC6156658
OpenAlexW2779331702

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.