Evidence map›Paper›PMID 29255009›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

FK506-Binding Protein 12.6/1b, a Negative Regulator of [Ca

John C Gant, Eric M Blalock, Kuey-Chu Chen, Inga Kadish, Olivier Thibault, Nada M Porter, Philip W Landfield

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Targeting of intracellular CaNPJ aging and mechanisms of disease · 2020
    Article
  8. Senescent neurophysiology: CaNeurobiology of learning and memory · 2019
    Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

John C GantDepartment of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, Kentucky 40536, and.
Eric M BlalockDepartment of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, Kentucky 40536, and.
Kuey-Chu ChenDepartment of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, Kentucky 40536, and.
Inga KadishDepartment of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama 35294.
Olivier ThibaultDepartment of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, Kentucky 40536, and.
Nada M PorterDepartment of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, Kentucky 40536, and.
Philip W LandfieldDepartment of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, Kentucky 40536, and pwland@uky.edu.
University of Kentucky · USUniversity of Alabama at Birmingham · US

Funding

HIPPOCAMPAL SYNAPTIC STRUCTURE--PHYSIOLOGY DURING AGINGR37AG004542 · NIA · UNIVERSITY OF KENTUCKY · PI LANDFIELD, PHILIP W. · 1998 to 2020
$7.1M
Psychosocial stress interactions with electrophysiology and brain agingR01AG037868 · NIA · UNIVERSITY OF KENTUCKY · PI BLALOCK, ERIC · 2011 to 2025
$3.5M
Metabolic syndrome and hippocampal Ca2+ dysregulation in aging-related memory decR01AG033649 · NIA · UNIVERSITY OF KENTUCKY · PI THIBAULT, OLIVIER · 2009 to 2019
$3.4M
Optimal Vitamin D Status as a Strategy to Rescue Cognitive AgingR21AG052050 · NIA · UNIVERSITY OF KENTUCKY · PI PORTER, NADA MICOVIC · 2016 to 2017
$414k
NIA NIH HHS R01 AG033649NIA NIH HHS R01 AG037868NIA NIH HHS R21 AG052050NIA NIH HHS R37 AG004542
6 · The paper itself

Abstract

Hippocampal overexpression of FK506-binding protein 12.6/1b (

Indexed as

AgingAnimalsCalcium SignalingGene Expression RegulationHippocampusMaleMemoryMemory DisordersRatsRats, Inbred F344Rats, TransgenicTacrolimus Binding ProteinsFKBP1b protein, ratTacrolimus Binding ProteinsagingcalciumcytoskeletonFKBP12.6microarrayryanodine receptor

Identifiers

PMID29255009
PMCPMC5783960
OpenAlexW2780223699

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.