Evidence map›Paper›PMID 29254993›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2018

Novel Targeting of Transcription and Metabolism in Glioblastoma.

Yu-Ting Su, Robert Chen, Herui Wang, Hua Song, Qi Zhang, Li-Yuan Chen, Hallie Lappin, Gabriel Vasconcelos, Adrian Lita, Dragan Maric and 11 more

Open access · greenAbstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 67 citations in OpenAlex.

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  19. CDK9 inhibitors in cancer research.RSC medicinal chemistry · 2022
    Review
  20. Anti-Vaccines · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 5 institutions in 1 country.

Yu-Ting SuNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
Robert ChenNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
Herui WangNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
Hua SongNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
Qi ZhangNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
Li-Yuan ChenCritical Care Medicine Department, Clinical Center, NIH, Bethesda, Maryland.
Hallie LappinNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
Gabriel VasconcelosNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
Adrian LitaNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
Dragan MaricFlow and Imaging Cytometry Core Facility, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, Maryland.
Aiguo LiNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
Orieta CelikuNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
Wei ZhangNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
Kristan MeetzeTragara Pharmaceuticals, Carlsbad, California.
Thomas EstokTragara Pharmaceuticals, Carlsbad, California.
Mioara LarionNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
Mones Abu-AsabSection of Histopathology, National Eye Institute, NIH, Bethesda, Maryland.
Zhengping ZhuangNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
Chunzhang YangNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
Mark R GilbertNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
Jing WuNeuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland. jing.wu3@nih.gov.
National Cancer Institute · USIonis Pharmaceuticals (United States) · USNational Eye Institute · USNational Institute of Neurological Disorders and Stroke · USNational Institutes of Health Clinical Center · US

Funding

Pre-clinical Translational Research FacilityZICBC011641 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WU, JING · 2015 to 2025
$22.2M
Discovering novel therapies for glioma patientsZIABC011840 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WU, JING · 2018 to 2025
$4.6M
Investigation on the biology of IDH mutant gliomaZIABC011684 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI YANG, CHUN ZHANG · 2016 to 2025
$3.6M
Intramural NIH HHS ZIA BC011840
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntineoplastic Combined Chemotherapy ProtocolsApoptosisBrainBrain NeoplasmsCell Line, TumorCell ProliferationDisease Models, AnimalDrug Evaluation, PreclinicalDrug SynergismEnergy MetabolismGlioblastomaHeterocyclic Compounds, 4 or More RingsHumansMiceMice, Inbred C57BL14-methyl-20-oxa-5,7,14,26-tetraazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaeneHeterocyclic Compounds, 4 or More RingsTemozolomide

Identifiers

PMID29254993
PMCPMC8108069
OpenAlexW2777560921

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.