Evidence map›Paper›PMID 29254944›Full record

ArticleGenome research2018

Conserved non-AUG uORFs revealed by a novel regression analysis of ribosome profiling data.

Pieter Spealman, Armaghan W Naik, Gemma E May, Scott Kuersten, Lindsay Freeberg, Robert F Murphy, Joel McManus

Open access · bronzeAbstract read
In one paragraph

Article in Genome research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 94 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Deciphering thebioRxiv : the preprint server for biology · 2024
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Pieter Spealman *Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA.
Armaghan W Naik *Computational Biology Department, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA.
Gemma E MayDepartment of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA.
Scott KuerstenIllumina, Incorporated, Madison, Wisconsin 53719, USA.
Lindsay FreebergIllumina, Incorporated, Madison, Wisconsin 53719, USA.
Robert F MurphyDepartment of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA.
Joel McManusDepartment of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA.
Carnegie Mellon University · USIllumina (United States) · US

Funding

TrainingP41GM103712 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FAEDER, JAMES · 2012 to 2021
$16.3M
Global analysis of uORF evolution and functionR01GM121895 · NIGMS · CARNEGIE-MELLON UNIVERSITY · PI MCMANUS, CHARLES JOEL · 2017 to 2021
$1.6M
NIGMS NIH HHS P41 GM103712NIGMS NIH HHS R01 GM121895
6 · The paper itself

Abstract

Upstream open reading frames (uORFs), located in transcript leaders (5' UTRs), are potent

Indexed as

Transcription, Genetic5' Untranslated RegionsCodon, InitiatorConserved SequenceOpen Reading FramesProtein BiosynthesisRegression AnalysisRibosomesRNA, MessengerSaccharomyces cerevisiae5' Untranslated RegionsCodon, InitiatorRNA, Messenger

Identifiers

PMID29254944
PMCPMC5793785
OpenAlexW2776644290

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.