Evidence map›Paper›PMID 29254513›Full record

ArticlePsychological medicine2018

The cross-national structure of mental disorders: results from the World Mental Health Surveys.

Peter de Jonge, Klaas J Wardenaar, Carmen C W Lim, Sergio Aguilar-Gaxiola, Jordi Alonso, Laura Helena Andrade, Brendan Bunting, Somnath Chatterji, Marius Ciutan, Oye Gureje and 11 more

Abstract read
In one paragraph

Article in Psychological medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
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  11. A Shared Multivariate Brain-Behavior Relationship in a Transdiagnostic Sample of Adolescents.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024
    Article
  12. The course of attention-deficit/hyperactivity disorder through midlife.European archives of psychiatry and clinical neuroscience · 2024
    Article
  13. The general factor of psychopathology (p): Choosing among competing models and interpreting p.Clinical psychological science : a journal of the Association for Psychological Science · 2024
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  15. Article
  16. Examination of the Factor Structure of Psychopathology in a Mozambican Sample.Clinical psychological science : a journal of the Association for Psychological Science · 2023
    Article
  17. Article
  18. Considerations toward an epigenetic and common pathways theory of mental disorder.Journal of psychopathology and clinical science · 2023
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  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Peter de JongeDevelopmental Psychology,Department of Psychology,Rijksuniversiteit Groningen,Groningen,Netherlands.
Klaas J WardenaarDepartment of Psychiatry,Interdisciplinary Center Psychopathology and Emotion Regulation,University Medical Center Groningen,Groningen,Netherlands.
Carmen C W LimDepartment of Psychological Medicine,University of Otago,Dunedin, Otago,New Zealand.
Sergio Aguilar-GaxiolaCenter for Reducing Health Disparities,UC Davis Health System,Sacramento, California,USA.
Jordi AlonsoHealth Services Research Unit,IMIM-Hospital del Mar Medical Research Institute,Barcelona,Spain.
Laura Helena AndradeNúcleo de Epidemiologia Psiquiátrica - LIM 23,Instituto de Psiquiatria Hospital das Clinicas da Faculdade de Medicina da Universidade,de São Paulo,Brazil.
Brendan BuntingSchool of Psychology,Ulster University,Londonderry,UK.
Somnath ChatterjiDepartment of Information,Evidence and Research, World Health Organization,Geneva,Switzerland.
Marius CiutanNational School of Public Health,Management and Development,Bucharest,Romania.
Oye GurejeDepartment of Psychiatry,University College Hospital,Ibadan,Nigeria.
Elie G KaramDepartment of Psychiatry and Clinical Psychology,St George Hospital University Medical Center, Balamand University,Faculty of Medicine,Beirut,Lebanon.
Sing LeeDepartment of Psychiatry,Chinese University of Hong Kong,Tai Po,Hong Kong.
Maria Elena Medina-MoraNational Institute of Psychiatry Ramon de la Fuente Muñiz,Mexico City,Mexico.
Jacek MoskalewiczInstitute of Psychiatry and Neurology,Warsaw,Poland.
Fernando Navarro-MateuUDIF-SM, Subdirección General de Planificación, Innovación y Cronicidad, Servicio Murciano de Salud; IMIB-Arrixaca; CIBERESP-Murcia,Murcia,Spain.
Beth-Ellen PennellSurvey Research Center,Institute for Social Research,University of Michigan,Ann Arbor, Michigan,USA.
Marina PiazzaUniversidad Cayetano Heredia,Lima,Peru.
José Posada-VillaColegio Mayor de Cundinamarca University, Faculty of Social Sciences,Bogota,Colombia.
Yolanda TorresCenter for Excellence on Research in Mental Health, CES University,Medellin,Colombia.
Ronald C KesslerDepartment of Health Care Policy,Harvard Medical School,Boston, Massachusetts,USA.
Kate ScottDepartment of Psychological Medicine,University of Otago,Dunedin, Otago,New Zealand.

Funding

EPIDEMIOLOGY-- NATIONAL COMORBIDITY SURVEY REPLICATIONU01MH060220 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 1999 to 2010
$18.7M
Risk Factors for Psychopathology in the WHO WMH SurveysR01MH070884 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 2005 to 2009
$6.0M
Social Role Disability and Mental-Physical Co-MorbidityR01MH069864 · NIMH · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI VON KORFF, MICHAEL R · 2004 to 2007
$2.2M
CROSS-NATIONAL STUDIES OF DRUG INVOLVEMENT: WMH2000R01DA016558 · NIDA · MICHIGAN STATE UNIVERSITY · PI ANTHONY, JAMES CHRISTOPHER · 2003 to 2008
$1.7M
Drug Dependence Epidemiology and EnviromicsK05DA015799 · NIDA · MICHIGAN STATE UNIVERSITY · PI ANTHONY, JAMES CHRISTOPHER · 2003 to 2015
$1.4M
World Mental Health Consortium Annual Meeting 2003-07R13MH066849 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HEERINGA, STEVEN G · 2003 to 2007
$735k
Lebanon-Epidemiology: The NCS Replication StudyR03TW006481 · FIC · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 2004 to 2006
$142k
FIC NIH HHS R03 TW006481NIDA NIH HHS K05 DA015799NIDA NIH HHS R01 DA016558NIMH NIH HHS R01 MH069864NIMH NIH HHS R01 MH070884NIMH NIH HHS R13 MH066849NIMH NIH HHS U01 MH060220World Health Organization 001
6 · The paper itself

Abstract

backgroundThe patterns of comorbidity among mental disorders have led researchers to model the underlying structure of psychopathology. While studies have suggested a structure including internalizing and externalizing disorders, less is known with regard to the cross-national stability of this model. Moreover, little data are available on the placement of eating disorders, bipolar disorder and psychotic experiences (PEs) in this structure.

methodsWe evaluated the structure of mental disorders with data from the World Health Organization Composite International Diagnostic Interview, including 15 lifetime mental disorders and six PEs. Respondents (n = 5478-15 499) were included from 10 high-, middle- and lower middle-income countries across the world aged 18 years or older. Confirmatory factor analyses (CFAs) were used to evaluate and compare the fit of different factor structures to the lifetime disorder data. Measurement invariance was evaluated with multigroup CFA (MG-CFA).

resultsA second-order model with internalizing and externalizing factors and fear and distress subfactors best described the structure of common mental disorders. MG-CFA showed that this model was stable across countries. Of the uncommon disorders, bipolar disorder and eating disorder were best grouped with the internalizing factor, and PEs with a separate factor.

conclusionsThese results indicate that cross-national patterns of lifetime common mental-disorder comorbidity can be explained with a second-order underlying structure that is stable across countries and can be extended to also cover less common mental disorders.

Indexed as

Mental DisordersModels, StatisticalAdultGlobal HealthHumansInterview, PsychologicalMental HealthPsychiatric Status Rating ScalesWorld Health Organizationcomorbidityepidemiologymental disorderspsychiatric disorders

Identifiers

PMID29254513
PMCPMC6008201

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