ArticleBMC infectious diseases2017
High prevalence of diarrheagenic Escherichia coli carrying toxin-encoding genes isolated from children and adults in southeastern Brazil.
Article in BMC infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 39 citations in OpenAlex.
- EnteroaggregativeEcoSal Plus · 2025Review
- Combating EnteroaggregativeAIMS microbiology · 2025Article
- DiarrheagenicInternational journal of molecular sciences · 2024Article
- Sequence-subtype association of multi-drug-resistant diarrheagenicIranian journal of microbiology · 2024Article
- Antimicrobial Profiles and Conventional PCR Assay of Shiga ToxigenicInfection and drug resistance · 2023Article
- Are non-lactose-fermentingAccess microbiology · 2023Article
- Antibiotic resistance, pathotypes, and pathogen-host interactions in Escherichia coli from hospital wastewater in Bulawayo, Zimbabwe.PloS one · 2023Article
- Transmission Media of Foodborne Diseases as an Index Prediction of DiarrheagenicInternational journal of environmental research and public health · 2020Observational
- Characterization and antibiotic resistance pattern of diffusely adherentNew microbes and new infections · 2020Article
- Virulence Characteristics and Antibiotic Resistance Profiles of Shiga Toxin-ProducingAntibiotics (Basel, Switzerland) · 2020Article
- Profiling Virulence and Antimicrobial Resistance Markers of EnterovirulentOsong public health and research perspectives · 2020Article
- Article
- Analysis of the Virulence Profile and Phenotypic Features of Typical and Atypical EnteroaggregativeFrontiers in cellular and infection microbiology · 2020Article
- EAST1 toxin: An enigmatic molecule associated with sporadic episodes of diarrhea in humans and animals.Journal of microbiology (Seoul, Korea) · 2019Review
- Diarrheagenic Escherichia coli in Costa Rican children: a 9-year retrospective study.BMC research notes · 2019Article
- Diversity of Virulence Genes in Multidrug ResistantInfection and drug resistance · 2019Article
- Typical and Atypical EnteroaggregativeFrontiers in microbiology · 2019Article
- Virulence gene profiles and molecular genetic characteristics of diarrheagenicGut pathogens · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundDiarrheagenic Escherichia coli (DEC) are important bacterial causes of childhood diarrhea in Brazil, but its impact in adults is unknown. This study aimed at investigating DEC among children and adults living in endemic areas.
methodsA total of 327 stools specimens were collected from children (n = 141) and adults (n = 186) with diarrhea attending health centers. Diarrheagenic E. coli (DEC) were identified by their virulence genes (multiplex polymerase chain reaction) and HEp-2 cell adherence patterns.
resultsDEC were detected in 56 (40%) children and 74 (39%) adults; enteroaggregative E. coli (EAEC) (23%) was the most prevalent pathotype, followed by diffusely adherent E. coli (DAEC) (13%), and occurred at similar frequencies in both diarrheal groups. Atypical enteropathogenic E. coli (aEPEC) strains were recovered more frequently from children (6%) than from adults (1%). Twenty-six percent of the EAEC were classified as typical EAEC possessing aggR gene, and carried the aap gene. EAEC strains carrying aggR-aap-aatA genes were significantly more frequent among children than adults (p < 0.05). DAEC strains possessing Afa/Dr. genes were detected from children (10%) and adults (6%). EAEC and DAEC strains harboring genes for the EAST1 (astA), Pet, Pic, and Sat toxins were common in both diarrheal groups. The astA and the porcine AE/associated adhesin (paa) genes were found in most of aEPEC strains. High levels of resistance to antimicrobial drugs were found among DAEC and aEPEC isolates.
conclusionThe results show a high proportion of EAEC and DAEC carrying toxin-encoding genes among adults with diarrhea.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.