Evidence map›Paper›PMID 29253872›Full record

Observational studyPloS one2017

Determinants for adherence to continuous positive airway pressure therapy in obstructive sleep apnea.

Anne Roed Jacobsen, Freja Eriksen, Rasmus Würgler Hansen, Mogens Erlandsen, Line Thorup, Mette Bjerre Damgård, Martin Glümer Kirkegaard, Klavs Würgler Hansen

Abstract readObservational Study
In one paragraph

Observational study in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Referral of adults with obstructive sleep apnea for surgical consultation: an American Academy of Sleep Medicine clinical practice guideline.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Guideline
  2. Referral of adults with obstructive sleep apnea for surgical consultation: an American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE assessment.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Effect of cloud-based sleep coaches on positive airway pressure adherence.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020
    Trial
  7. Trial
  8. NightBalance Sleep Position Treatment Device Versus Auto-Adjusting Positive Airway Pressure for Treatment of Positional Obstructive Sleep Apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019
    Trial
  9. Navigating sleep apnea in Scandinavia - a journey of contrasts.International journal of qualitative studies on health and well-being · 2026
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Using Cannabis and CBD to Sleep: An Updated Review.Current psychiatry reports · 2024
    Review
  18. Article
  19. Article
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anne Roed JacobsenDiagnostic Centre, Regional Hospital Silkeborg, Silkeborg, Denmark.ORCID http://orcid.org/0000-0002-9204-0864
Freja EriksenDiagnostic Centre, Regional Hospital Silkeborg, Silkeborg, Denmark.
Rasmus Würgler HansenDiagnostic Centre, Regional Hospital Silkeborg, Silkeborg, Denmark.
Mogens ErlandsenSection for Biostatistics, Department of Public Health, Aarhus University, Aarhus, Denmark.
Line ThorupInterdisciplinary Research Unit, Elective Surgery Centre, Regional Hospital Silkeborg, Silkeborg, Denmark.
Mette Bjerre DamgårdSleep Disorders Clinic, Elective Surgery Centre, Regional Hospital Silkeborg, Silkeborg, Denmark.
Martin Glümer KirkegaardSleep Disorders Clinic, Elective Surgery Centre, Regional Hospital Silkeborg, Silkeborg, Denmark.
Klavs Würgler HansenDiagnostic Centre, Regional Hospital Silkeborg, Silkeborg, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundContinuous positive airway pressure (CPAP) therapy is an efficacious treatment for patients diagnosed with obstructive sleep apnea (OSA). However, there are only few data on long-term adherence. The aim of this study is to quantify the extent of non-adherence and describe the clinical characteristics.

methodsA retrospective study including 695 patients with newly diagnosed OSA and prescribed CPAP therapy within an inclusion period of 14 months. All patients were offered free of charge individually adjusted CPAP therapy. Data on comorbidity, medication, BMI and Epworth Sleepiness Score (ESS) were obtained by questionnaires and consultation with an otorhinolaryngeal specialist.

resultsThe median follow-up time after initiating CPAP therapy was 3.0 (range 2.4-3.6) years. An adherence rate of 89% was found for severe OSA, 71% for moderate OSA and 55% for mild OSA. 18% initiated humidification. Patients adherent to CPAP had a significantly higher Body Mass Index (BMI), Apnea Hypopnea Index (AHI), Oxygen Desaturation Index (ODI) and ESS compared to non-adherent patients. Furthermore, adherence was associated with a higher frequency of observed interrupted breathing, a less frequent use of hypnotic drugs, fewer smokers, and they were more often offered humidification. Age, gender and comorbidity were not significantly associated with adherence. In a Cox model only AHI (Hazard Ratio (HR) 0.963, p < 0.001), ESS (HR 0.939, p = 0.001) and smoking (HR 1.576, p = 0.022) were independently associated with CPAP non-adherence.

conclusionsThe severity of OSA, subjective daytime sleepiness and smoking status are independently related to adherence to CPAP therapy.

Indexed as

Patient ComplianceAgedBody Mass IndexContinuous Positive Airway PressureFemaleHumansKaplan-Meier EstimateMaleMiddle AgedPolysomnographyProportional Hazards ModelsRetrospective StudiesSeverity of Illness IndexSleepSleep Apnea, ObstructiveSmoking

Identifiers

PMID29253872
PMCPMC5734784

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.