ArticlePloS one2017
Aedes aegypti resistance development to commonly used insecticides in Jakarta, Indonesia.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 70 citations in OpenAlex.
- Review
- Insecticide resistance levels, spatial distribution, and kdr mutations in the dengue vector Aedes albopictus of Hong Kong.PLoS neglected tropical diseases · 2025Article
- Resistance status ofNarra J · 2025Review
- A systematic review of insecticide resistance inVeterinary world · 2025Review
- Insecticide Resistance inInsects · 2024Article
- Comparative transcriptional analysis between susceptible and resistant populations of Aedes (Stegomyia) aegypti (Linnaeus, 1762) after malathion exposure.Molecular genetics and genomics : MGG · 2024Article
- Effects of the El Niño-Southern Oscillation and seasonal weather conditions on Aedes aegypti infestation in the State of São Paulo (Brazil): A Bayesian spatio-temporal study.PLoS neglected tropical diseases · 2024Article
- Biotechnological Potential of Microorganisms for Mosquito Population Control and Reduction in Vector Competence.Insects · 2023Review
- Worldwide Status of Insecticide Resistance ofJournal of arthropod-borne diseases · 2023Review
- Assessment of susceptibleHeliyon · 2022Article
- Updating the Insecticide Resistance Status ofTropical medicine and infectious disease · 2022Review
- Insecticide Resistance Profiles and Synergism of Field Aedes aegypti from Indonesia.PLoS neglected tropical diseases · 2022Article
- Knockdown resistance (kdr) gene of Aedes aegypti in Malaysia with the discovery of a novel regional specific point mutation A1007G.Parasites & vectors · 2022Article
- Temporal Evaluation of Insecticide Resistance in Populations of the Major Arboviral VectorInsects · 2022Article
- Dengue fever and insecticide resistance in Aedes mosquitoes in Southeast Asia: a review.Parasites & vectors · 2021Review
- Frequency of kdr mutations in the voltage-sensitive sodium channel (VParasites & vectors · 2020Article
- The V1016G mutation of the voltage-gated sodium channel (VGSC) gene contributes to the insecticide resistance of Aedes aegypti from Makassar, Indonesia.Parasitology research · 2020Article
- Article
- The F1534C voltage-sensitive sodium channel mutation confers 7- to 16-fold resistance to pyrethroid insecticides in Aedes aegypti.Pest management science · 2020Article
- Chronology of sodium channel mutations associated with pyrethroid resistance in Aedes aegypti.Archives of insect biochemistry and physiology · 2020Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aedes aegypti is the primary vector of various relevant arthropod-borne viral infectious diseases worldwide. The mosquito control is still mainly performed by using insecticides but their effectiveness is increasingly questioned nowadays. We here conducted a study on Ae. aegypti resistance development towards several commonly used insecticides in the capital city of Jakarta, Indonesia. In order to achieve this goal, Ae. aegypti eggs from Jakarta were collected with ovitraps and hatched in the insectary of the Gadjah Mada University, Indonesia. The F0 generations were used for WHO resistance tests and knockdown resistance (kdr) assays. Presented results clearly showed that there was resistance development of Ae. aegypti populations to the here tested pyrethroid insecticides (i. e. permethrin). Observed mortalities were less than 90% with highest resistance against 0.75% permethrin concentrations. Furthermore, a significant association of V1016G gene mutations with resistance phenotypes to 0.75% permethrin was observed. Nevertheless, the F1534C mutation did not show a significant correlation to resistance development. In conclusion, our results show that populations of Ae. aegypti mosquitoes within the city of Jakarta have developed resistance against several routinely used pyrethroid insecticides in local performed control programs. Thus, the regular verification/assessment of resistance development status will hopefully help in the future to assist local public health authorities in their mosquito control programs by recommending and managing the rotation of different routinely used insecticides with diverse effector mechanisms in order to delay Ae. aegypti resistance development.
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