ArticleInfection and immunity1989
Effect of immunoglobulin M from normal human serum on Leishmania donovani promastigote agglutination, complement-mediated killing, and phagocytosis by human monocytes.
Article in Infection and immunity, 1989. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 49 citations in OpenAlex.
- Article
- Total serumiScience · 2023Article
- Innate immunity against Leishmania infections.Cellular microbiology · 2015Review
- Human poly- and cross-reactive anti-viral antibodies and their impact on protection and pathology.Immunologic research · 2012Review
- Maternal anti-protein Z antibodies in pregnancies complicated by pre-eclampsia, SGA and fetal death.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2009Article
- A critical role for induced IgM in the protection against West Nile virus infection.The Journal of experimental medicine · 2003Article
- Pathogenesis of flavivirus encephalitis.Advances in virus research · 2003Review
- Complement interaction with trypanosomatid promastigotes in normal human serum.The Journal of experimental medicine · 2002Article
- Immune adherence-mediated opsonophagocytosis: the mechanism of Leishmania infection.The Journal of experimental medicine · 1999Article
- Cationic glycoproteins in sera of patients with acute infections identified as kappa light chain glycosylated IgG.Medical microbiology and immunology · 1993Article
- Purification and characterization of alpha-toxin produced by Clostridium novyi type A.Infection and immunity · 1993Article
- Specific and natural antibody production during Salmonella typhimurium infection in genetically susceptible and resistant mice.Immunology · 1993Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Serum from healthy, nonimmune humans contained immunoglobulin M (IgM) antibodies that agglutinated Leishmania donovani promastigotes, activated complement, and enhanced promastigote ingestion by human monocytes. The findings indicate that IgM antibodies have the capacity to affect the initial interaction of L. donovani promastigotes with human host defenses.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.