Evidence map›Paper›PMID 29252168›Full record

ArticleJournal of psychiatry & neuroscience : JPN2018

Clozapine, elevated heart rate and QTc prolongation.

David D Kim, Randall F White, Alasdair M Barr, William G Honer, Ric M Procyshyn

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of psychiatry & neuroscience : JPN, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David D KimFrom the Department of Anesthesiology, Pharmacology & Therapeutics, University of British Columbia, Vancouver, BC, Canada (Kim, Barr); the Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada (White, Honer, Procyshyn); the B.C. Psychosis Program, UBC Hospital, Vancouver, BC, Canada (White, Honer, Procyshyn); and the British Columbia Mental Health and Addictions Research Institute ,Vancouver, BC, Canada (Barr, Honer, Procyshyn).
Randall F WhiteFrom the Department of Anesthesiology, Pharmacology & Therapeutics, University of British Columbia, Vancouver, BC, Canada (Kim, Barr); the Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada (White, Honer, Procyshyn); the B.C. Psychosis Program, UBC Hospital, Vancouver, BC, Canada (White, Honer, Procyshyn); and the British Columbia Mental Health and Addictions Research Institute ,Vancouver, BC, Canada (Barr, Honer, Procyshyn).
Alasdair M BarrFrom the Department of Anesthesiology, Pharmacology & Therapeutics, University of British Columbia, Vancouver, BC, Canada (Kim, Barr); the Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada (White, Honer, Procyshyn); the B.C. Psychosis Program, UBC Hospital, Vancouver, BC, Canada (White, Honer, Procyshyn); and the British Columbia Mental Health and Addictions Research Institute ,Vancouver, BC, Canada (Barr, Honer, Procyshyn).
William G HonerFrom the Department of Anesthesiology, Pharmacology & Therapeutics, University of British Columbia, Vancouver, BC, Canada (Kim, Barr); the Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada (White, Honer, Procyshyn); the B.C. Psychosis Program, UBC Hospital, Vancouver, BC, Canada (White, Honer, Procyshyn); and the British Columbia Mental Health and Addictions Research Institute ,Vancouver, BC, Canada (Barr, Honer, Procyshyn).
Ric M ProcyshynFrom the Department of Anesthesiology, Pharmacology & Therapeutics, University of British Columbia, Vancouver, BC, Canada (Kim, Barr); the Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada (White, Honer, Procyshyn); the B.C. Psychosis Program, UBC Hospital, Vancouver, BC, Canada (White, Honer, Procyshyn); and the British Columbia Mental Health and Addictions Research Institute ,Vancouver, BC, Canada (Barr, Honer, Procyshyn).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antipsychotic AgentsClozapineElectrocardiographyHeart RateHumansLong QT SyndromeMaleMiddle AgedSchizophreniaAntipsychotic AgentsClozapine

Identifiers

PMID29252168
PMCPMC5747540

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.