Evidence map›Paper›PMID 29252139›Full record

ArticleLymphatic research and biology2017

Temporal Dynamics of the Rat Thoracic Duct Contractility in the Presence of Imposed Flow.

Olga Yu Gasheva, Jerome P Trzeciakowski, Anatoliy A Gashev, David C Zawieja

Open access · greenAbstract read
In one paragraph

Article in Lymphatic research and biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Olga Yu GashevaDepartment of Medical Physiology, College of Medicine, Texas A&M University Health Science Center , Temple/College Station, Texas.
Jerome P TrzeciakowskiDepartment of Medical Physiology, College of Medicine, Texas A&M University Health Science Center , Temple/College Station, Texas.
Anatoliy A GashevDepartment of Medical Physiology, College of Medicine, Texas A&M University Health Science Center , Temple/College Station, Texas.
David C ZawiejaDepartment of Medical Physiology, College of Medicine, Texas A&M University Health Science Center , Temple/College Station, Texas.
Texas A&M University System · US

Funding

Transport Phenomena in the Lymphatic SystemU01HL123420 · NHLBI · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI MOORE, JAMES E, ZAWIEJA, DAVID CARL · 2014 to 2018
$2.9M
Influences of Lymph Flow on the Lymphatic PumpR01HL070308 · NHLBI · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ZAWIEJA, DAVID CARL · 2003 to 2010
$2.4M
NHLBI NIH HHS R01 HL070308NHLBI NIH HHS U01 HL123420
6 · The paper itself

Abstract

backgroundThe initial periods of increased flow inside lymphatic vessels demonstrate specific temporary patterns of self-tuning of lymphatic vessel contractility that are heterogeneous across regional lymphatic networks. The current literature primarily refers to the immediate and fast reactions of the lymphangions to increases in basal flow. Until now, there were no available data on how the lymphatic vessels react to comparatively longer periods of imposed flow. METHODS AND

resultsIn this study, we measured and analyzed the contractility of the rat thoracic duct segments, isolated, cannulated, and pressurized at 3 cm H

conclusionsOur new findings provide a better understanding of how lymphatic contractility changes during the development of prolonged periods of steady lymph flow. The latter may occur during the initial phases of development of an inflammatory-related tissue edema.

Indexed as

VasoconstrictionAnimalsHemodynamicsMaleRatsThoracic DuctTime Factorsimposed flowlymphatic contractilitythoracic duct

Identifiers

PMID29252139
PMCPMC5734147
OpenAlexW2779410142

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.