Evidence map›Paper›PMID 29251975›Full record

Trial reportExperimental and clinical psychopharmacology2017

Contingency management targeting abstinence is effective in reducing depressive and anxiety symptoms among crack cocaine-dependent individuals.

André Q C Miguel, Clarice S Madruga, Hugo Cogo-Moreira, Rodolfo Yamauchi, Viviane Simões, Ariadne Ribeiro, Claudio J da Silva, Andrew Fruci, Michael McDonell, Sterling McPherson and 2 more

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Experimental and clinical psychopharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Psychosocial interventions for stimulant use disorder.The Cochrane database of systematic reviews · 2024
    Pooled it
  4. Article
  5. Article
  6. Depression, anxiety, and drug usage history indicators among institutionalized juvenile offenders of Brasilia.Psicologia, reflexao e critica : revista semestral do Departamento de Psicologia da UFRGS · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Crack cocaine users views regarding treatment with contingency management in Brazil.Substance abuse treatment, prevention, and policy · 2018
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

André Q C MiguelNational Institute of Policies on Alcohol and Drugs (INPAD).ORCID 0000-0003-3203-3889
Clarice S MadrugaNational Institute of Policies on Alcohol and Drugs (INPAD).ORCID 0000-0003-1993-1748
Hugo Cogo-MoreiraDepartment of Psychiatry and Medical Psychology.
Rodolfo YamauchiNational Institute of Policies on Alcohol and Drugs (INPAD).
Viviane SimõesNational Institute of Policies on Alcohol and Drugs (INPAD).
Ariadne RibeiroNational Institute of Policies on Alcohol and Drugs (INPAD).
Claudio J da SilvaNational Institute of Policies on Alcohol and Drugs (INPAD).
Andrew FruciProgram of Excellence in Addictions Research, Washington State University.
Michael McDonellProgram of Excellence in Addictions Research, Washington State University.
Sterling McPhersonProgram of Excellence in Addictions Research, Washington State University.
John M RollProgram of Excellence in Addictions Research, Washington State University.
Ronaldo R LaranjeiraNational Institute of Policies on Alcohol and Drugs (INPAD).
National Institute on Alcohol Abuse and Alcoholism · USInstitute for Research, Education and Training in Addictions · US

Funding

CLINICAL TRIALS NETWORK: PACIFIC NORTHWEST NODEU10DA013714 · NIDA · UNIVERSITY OF WASHINGTON · PI DONOVAN, DENNIS MICHAEL, ROLL, JOHN M. · 2001 to 2015
$25.5M
Fundação de Amparo a Pesquisa de São Paulo (FAPESP)NIDA NIH HHS U10 DA013714
6 · The paper itself

Abstract

Although contingency management (CM) is effective in promoting abstinence and treatment retention among crack cocaine users who meet the criteria for cocaine dependence, less is known about its off-target effects. In this secondary analysis, we evaluated the impact of CM on depressive and anxiety symptoms in a sample of cocaine-dependent individuals under treatment. Sixty-five crack cocaine users who met the criteria for cocaine dependence were randomly assigned to receive 12 weeks of standard treatment alone (STA; n = 32) or 12 weeks of standard treatment plus CM (STCM; n = 33). The outcome measures of the secondary analysis were depressive and anxiety symptoms assessed with the Beck Depression Inventory-II (BDI-II) and the Beck Anxiety Inventory (BAI). At baseline, 59 (90.8%) of the participants reported at least mild depressive symptoms and 47 (72.5%) reported at least mild anxiety symptoms. The mean BDI-II (24.5 ± 12.1) and BAI (20.7 ± 13.5) scores in the sample as a whole was moderate. After treatment, the reported levels of depressive symptoms (β = -9.6, p < .05) and anxiety symptoms (β = -9.9, p < .05) were lower among the individuals receiving STCM than among those receiving STA. This study provides evidence that an STCM intervention targeting crack cocaine abstinence also produces significant reductions in depressive and anxiety symptoms. This low cost intervention also demonstrated significant promise and optimization potential for crack cocaine users in a setting of scarce resources and high mental health comorbidity. Relevance Statement: We found that the prevalence of depressive and anxiety symptoms were extremely high among crack cocaine users, and that, among such individuals, contingency management (CM) reduced depressive and anxiety symptomatology to a greater degree than did standard treatment. Our results suggest that CM targeting crack cocaine abuse can have off-target effects on psychiatric symptomatology. (PsycINFO Database Record

Indexed as

Crack CocaineReinforcement, PsychologyAdolescentAdultAgedAnxietyCocaine-Related DisordersDepressionFemaleHumansMaleMiddle AgedPsychiatric Status Rating ScalesPsychotherapy, GroupTreatment OutcomeYoung AdultCrack Cocaine

Identifiers

PMID29251975
PMCPMC5737792
OpenAlexW2779779951

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.