ReviewBirth defects research2017
Taurine, caffeine, and energy drinks: Reviewing the risks to the adolescent brain.
Review in Birth defects research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 108 citations in OpenAlex.
- Trial
- Energy Drink Use and Adolescent Sleep Debt: Implications for Obesity, Cognition, and Physical Activity.Nutrients · 2026Review
- Eating Habits, Body Weight Perception, and Psycho-Emotional Factors Among Romanian University Students: A Cross-Sectional Study.Nutrients · 2026Observational
- Concomitant intake of high levels of monosodium glutamate and taurine induces adverse effects in the rat brain.Toxicology reports · 2026Article
- Prevalence of Bruxism Among Young Adult Energy Drink Consumers in Jordan.Journal of clinical medicine · 2025Article
- Predictors of caffeine consumption patterns in high school athletes.Journal of the International Society of Sports Nutrition · 2025Article
- Exploring perception types regarding the effects of energy drink consumption among South Korean male adolescents: a Q-methodology study.Child health nursing research · 2025Article
- Energy Drink Exposures and Trends in Children and Young Adults Reported to the National Poison Data System.Progress in pediatric cardiology · 2025Article
- Factors Influencing Energy Drink Usage Amongst Pupils in the Mahikeng Sub-District, Northwest.Nutrients · 2025Article
- Evaluating chemical effects on human neural cells through calcium imaging and deep learning.iScience · 2024Article
- Article
- Article
- Energy drinks in Tamale: Understanding youth perceptions, consumption patterns, and related factors.PloS one · 2024Article
- Age-related differences in affective behaviors in mice: possible role of prefrontal cortical-hippocampal functional connectivity and metabolomic profiles.Frontiers in aging neuroscience · 2024Article
- B Vitamins, Glucoronolactone and the Immune System: Bioavailability, Doses and Efficiency.Nutrients · 2023Review
- Alcohol and energy drinks: individual contribution of common ingredients on ethanol-induced behaviour.Frontiers in behavioral neuroscience · 2023Review
- Energy drinks at adolescence: Awareness or unawareness?Frontiers in behavioral neuroscience · 2023Review
- Caffeine, D-glucuronolactone and Taurine Content in Energy Drinks: Exposure and Risk Assessment.Nutrients · 2022Article
- Central Nervous System Stimulants Limit Caffeine Transport at the Blood-Cerebrospinal Fluid Barrier.International journal of molecular sciences · 2022Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Energy drinks are emerging as a major component of the beverage market with sales projected to top $60 billion globally in the next five years. Energy drinks contain a variety of ingredients, but many of the top-selling brands include high doses of caffeine and the amino acid taurine. Energy drink consumption by children has raised concerns, due to potential caffeine toxicity. An additional risk has been noted among college-aged consumers of energy drinks who appear at higher risk of over-consumption of alcohol when the two drinks are consumed together. The differential and combinatorial effects of caffeine and taurine on the developing brain are reviewed here with an emphasis on the adolescent brain, which is still maturing. Key data from animal studies are summarized to highlight both reported benefits and adverse effects reported following acute and chronic exposures. The data suggest that age is an important factor in both caffeine and taurine toxicity. Although the aged or diseased brain might benefit from taurine or caffeine supplementation, it appears that adolescents are not likely to benefit from supplementation and may, in fact, suffer ill effects from chronic ingestion of high doses. Additional work is needed though to address gaps in our understanding of how taurine affects females, since the majority of animal studies focused exclusively on male subjects.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.