Evidence map›Paper›PMID 29251824›Full record

ArticleThoracic cancer2018

Dual drive coexistence of EML4-ALK and TPM3-ROS1 fusion in advanced lung adenocarcinoma.

You-Cai Zhu, Xing-Hui Liao, Wen-Xian Wang, Chun-Wei Xu, Wu Zhuang, Jian-Guo Wei, Kai-Qi Du

Open access · goldAbstract readCase Reports
In one paragraph

Article in Thoracic cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

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  9. Association Analysis of Driver Gene-Related Genetic Variants Identified Novel Lung Cancer Susceptibility Loci with 20,871 Lung Cancer Cases and 15,971 Controls.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

You-Cai ZhuChest Disease Diagnosis and Treatment Center, Zhejiang Rongjun Hospital, Jiaxing, China.
Xing-Hui LiaoTumor Molecular Laboratory, Zhejiang Rongjun Hospital, Jiaxing, China.
Wen-Xian WangDepartment of Chemotherapy, Zhejiang Cancer Hospital, Hangzhou, China.ORCID 0000-0002-3047-4149
Chun-Wei XuDepartment of Pathology, Fujian Cancer Hospital, Fujian Medical University Cancer Hospital, Fuzhou, China.ORCID 0000-0002-9021-6731
Wu ZhuangDepartment of Medical Thoracic Oncology, Fujian Cancer Hospital, Fujian Medical University Cancer Hospital, Fuzhou, China.
Jian-Guo WeiDepartment of Pathology, Shaoxing People's Hospital, Shaoxing, China.
Kai-Qi DuChest Disease Diagnosis and Treatment Center, Zhejiang Rongjun Hospital, Jiaxing, China.
First Hospital of Jiaxing · CNFujian Medical University · CNShaoxing People's Hospital · CNZhejiang Cancer Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of concomitant EML4-ALK and TPM3-ROS1 fusion in non-small cell lung cancer (NSCLC) in a 47-year-old Chinese man and review the clinical characteristics of this type double of fusion. The patient presented with a local tumor of the left upper lobe and underwent thoracoscopy. Postoperative surgical pathologic staging revealed T

Indexed as

AdenocarcinomaAdenocarcinoma of LungErbB ReceptorsHigh-Throughput Nucleotide SequencingHumansLung NeoplasmsMaleMiddle AgedMutationNeoplasm StagingOncogene Proteins, FusionProtein-Tyrosine KinasesProto-Oncogene ProteinsTropomyosinEGFR protein, humanEML4-ALK fusion protein, humanErbB ReceptorsOncogene Proteins, FusionProtein-Tyrosine KinasesProto-Oncogene ProteinsROS1 protein, humanTPM3 protein, humanTropomyosinAnaplastic lymphoma kinaseconcomitantlung cancerROS1

Identifiers

PMID29251824
PMCPMC5792730
OpenAlexW2776305367

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.