Evidence map›Paper›PMID 29251718›Full record

ArticleNature chemical biology2018

A role for 2-Cys peroxiredoxins in facilitating cytosolic protein thiol oxidation.

Sarah Stöcker, Michael Maurer, Thomas Ruppert, Tobias P Dick

Open access · greenAbstract read
In one paragraph

Article in Nature chemical biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

96 citing papers in PubMed, 199 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Redox Control of Skeletal Muscle Function and Adaptations to Exercise.Advances in experimental medicine and biology · 2025
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Proteome-wide tagging with an HProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  18. Article
  19. Review
  20. Article

36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sarah StöckerDivision of Redox Regulation, DKFZ-ZMBH Alliance, German Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID 0000-0002-6145-7173
Michael MaurerDivision of Redox Regulation, DKFZ-ZMBH Alliance, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Thomas RuppertCore Facility for Mass Spectrometry and Proteomics, DKFZ-ZMBH Alliance, Zentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), Heidelberg, Germany.
Tobias P DickDivision of Redox Regulation, DKFZ-ZMBH Alliance, German Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID 0000-0003-1367-973X
German Cancer Research Center · DEHeidelberg University · DE

Funding

European Research Council 742039
6 · The paper itself

Abstract

Hydrogen peroxide (H

Indexed as

CysteineCytosolDisulfidesHEK293 CellsHumansHydrogen PeroxideKineticsOxidation-ReductionOxygenPeroxiredoxinsRecombinant ProteinsRNA, Small InterferingSignal TransductionSulfhydryl CompoundsThioredoxinsCysteineDisulfidesHydrogen PeroxideOxygenPeroxiredoxinsRecombinant ProteinsRNA, Small InterferingSulfhydryl CompoundsThioredoxins

Identifiers

PMID29251718
PMCPMC5863949
OpenAlexW2778452486

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.