Evidence map›Paper›PMID 29250531›Full record

ArticleNeuroscience journal2017

Impact of Blood Vessel Quantity and Vascular Expression of CD133 and ICAM-1 on Survival of Glioblastoma Patients.

Ave Minajeva, Marju Kase, Mikk Saretok, Aidi Adamson-Raieste, Sandra Kase, Kristi Niinepuu, Markus Vardja, Toomas Asser, Jana Jaal

Abstract read
In one paragraph

Article in Neuroscience journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ave MinajevaFaculty of Medicine, University of Tartu, Tartu, Estonia.ORCID 0000-0003-0256-1410
Marju KaseEast-Tallinn Central Hospital, Tallinn, Estonia.
Mikk SaretokFaculty of Medicine, University of Tartu, Tartu, Estonia.
Aidi Adamson-RaiesteFaculty of Medicine, University of Tartu, Tartu, Estonia.
Sandra KaseRiga Stradiņš University, Riga, Latvia.
Kristi NiinepuuHaematology and Oncology Clinic, Department of Radiotherapy and Oncological Therapy, Tartu University Hospital, Tartu, Estonia.
Markus VardjaHaematology and Oncology Clinic, Department of Radiotherapy and Oncological Therapy, Tartu University Hospital, Tartu, Estonia.
Toomas AsserFaculty of Medicine, University of Tartu, Tartu, Estonia.
Jana JaalFaculty of Medicine, University of Tartu, Tartu, Estonia.ORCID 0000-0002-1385-7391

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma (GB) is the most angiogenic tumor. Nevertheless, antiangiogenic therapy has not shown significant clinical efficacy. The aim of this study was to assess blood vessel characteristics on survival of GB patients. Surgically excised GB tissues were histologically examined for overall proportion of glomeruloid microvascular proliferation (MP) and the total number of blood vessels. Also, immunohistochemical vascular staining intensities of CD133 and ICAM-1 were determined. Vessel parameters were correlated with patients' overall survival. The survival time depended on the number of blood vessels (

Identifiers

PMID29250531
PMCPMC5698821

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.