Evidence map›Paper›PMID 29250492›Full record

ArticleFrontiers in cellular and infection microbiology2017

Transcriptional Immunoprofiling at the Tick-Virus-Host Interface during Early Stages of Tick-Borne Encephalitis Virus Transmission.

Saravanan Thangamani, Meghan E Hermance, Rodrigo I Santos, Mirko Slovak, Dar Heinze, Steven G Widen, Maria Kazimirova

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
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  17. Observational
  18. Subversion of Host Innate Immunity byFrontiers in immunology · 2021
    Article
  19. Utilization of RNAFrontiers in cellular and infection microbiology · 2020
    Article
  20. Tick-Borne Encephalitis Virus Infection Alters the Sialome ofFrontiers in cellular and infection microbiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Saravanan ThangamaniDepartment of Pathology, The University of Texas Medical Branch, Galveston, TX, United States.
Meghan E HermanceDepartment of Pathology, The University of Texas Medical Branch, Galveston, TX, United States.
Rodrigo I SantosDepartment of Pathology, The University of Texas Medical Branch, Galveston, TX, United States.
Mirko SlovakInstitute of Zoology, Slovak Academy of Sciences, Bratislava, Slovakia.
Dar HeinzeDepartment of Surgery, Center for Regenerative Medicine, Boston University and Boston Medical Center, Boston, MA, United States.
Steven G WidenDepartment of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, TX, United States.
Maria KazimirovaInstitute of Zoology, Slovak Academy of Sciences, Bratislava, Slovakia.

Funding

TICK DETERMINANTS OF POWASSAN VIRUS TRANSMISSIONR01AI127771 · NIAID · UPSTATE MEDICAL UNIVERSITY · PI THANGAMANI, SARAVANAN · 2017 to 2021
$2.0M
Development of a Tick Transmission Model for Heartland Virus PathogenesisR21AI113128 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI THANGAMANI, SARAVANAN · 2015 to 2016
$426k
NIAID NIH HHS R01 AI127771NIAID NIH HHS R21 AI113128
6 · The paper itself

Abstract

Emerging and re-emerging diseases transmitted by blood feeding arthropods are significant global public health problems. Ticks transmit the greatest variety of pathogenic microorganisms of any blood feeding arthropod. Infectious agents transmitted by ticks are delivered to the vertebrate host together with saliva at the bite site. Tick salivary glands produce complex cocktails of bioactive molecules that facilitate blood feeding and pathogen transmission by modulating host hemostasis, pain/itch responses, wound healing, and both innate and adaptive immunity. In this study, we utilized Illumina Next Generation Sequencing to characterize the transcriptional immunoprofile of cutaneous immune responses to

Indexed as

AnimalsChemokinesCytokinesDisease Models, AnimalEncephalitis, Tick-BorneEncephalitis Viruses, Tick-BorneFemaleFlavivirusGene ExpressionHigh-Throughput Nucleotide SequencingHistocompatibility Antigens Class IIHost-Parasite InteractionsImmunohistochemistryIxodesMiceMice, Inbred BALB CChemokinesCytokinesHistocompatibility Antigens Class IIcutaneousflavivirusimmune responseIxodes ricinusTBEVtick

Identifiers

PMID29250492
PMCPMC5716978

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.