Evidence map›Paper›PMID 29250491›Full record

ArticleFrontiers in cellular and infection microbiology2017

Human Primary Epithelial Cells Acquire an Epithelial-Mesenchymal-Transition Phenotype during Long-Term Infection by the Oral Opportunistic Pathogen,

Jungnam Lee, JoAnn S Roberts, Kalina R Atanasova, Nityananda Chowdhury, Kyudong Han, Özlem Yilmaz

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed, 2 pooled it
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 2 syntheses or guidelines pooled it, 134 citations in OpenAlex.

  1. Pooled it
  2. Distinct gene expression characteristics in epithelial cell-International journal of medical sciences · 2019
    Pooled it
  3. Gut microbes · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
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  12. The Role ofCancers · 2025
    Review
  13. Article
  14. The multi-kingdom cancer microbiome.Nature microbiology · 2025
    Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article

32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Jungnam LeeDivision of Pulmonary, Critical Care and Sleep Medicine, University of Florida, Gainesville, FL, United States.
JoAnn S RobertsDepartment of Oral Health Sciences, College of Dental Medicine, Medical University of South Carolina, Charleston, SC, United States.
Kalina R AtanasovaDepartment of Periodontology, University of Florida, Gainesville, FL, United States.
Nityananda ChowdhuryDepartment of Oral Health Sciences, College of Dental Medicine, Medical University of South Carolina, Charleston, SC, United States.
Kyudong HanDepartment of Nanobiomedical Science, BK21 PLUS NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan, South Korea.
Özlem YilmazDepartment of Oral Health Sciences, College of Dental Medicine, Medical University of South Carolina, Charleston, SC, United States.
Medical University of South Carolina · USUniversity of Florida · USTheragen · KR

Funding

T-COHR: Training in Craniofacial and Oral Health ResearchT32DE017551 · NIDCR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI YAO, HAI · 2006 to 2025
$10.3M
Comprehensive Training Program in Oral BiologyT90DE021990 · NIDCR · UNIVERSITY OF FLORIDA · PI Jose A Lemos · 2011 to 2026
$8.2M
Role of the Spx Regulator in Streptococcus mutansR01DE019783 · NIDCR · UNIVERSITY OF ROCHESTER · PI LEMOS, JOSE A · 2010 to 2020
$3.7M
Modulation of epithelial cell response by P. gingivalisR01DE016593 · NIDCR · UNIVERSITY OF FLORIDA · PI YILMAZ, OZLEM · 2006 to 2016
$3.3M
Modulation of Epithelial Cell Response by P. gingivalisR56DE016593 · NIDCR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI YILMAZ, OZLEM · 2019 to 2019
$355k
NIDCR NIH HHS R01 DE016593NIDCR NIH HHS R01 DE019783NIDCR NIH HHS R56 DE016593NIDCR NIH HHS T32 DE017551NIDCR NIH HHS T90 DE021990
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

PhenotypeApoptosisbeta CateninCadherinsCarcinoma, Squamous CellCell Line, TumorCell MovementCoinfectionEpithelial CellsFusobacterium nucleatumGene Expression RegulationGlycogen Synthase KinasesHost-Pathogen InteractionsHumansMatrix Metalloproteinase 2Matrix Metalloproteinase 7beta CateninCadherinsCTNNB1 protein, humanGlycogen Synthase KinasesMatrix Metalloproteinase 2Matrix Metalloproteinase 7Matrix Metalloproteinase 9MitomycinSNAI1 protein, humanSnail Family Transcription FactorsTranscription FactorsVimentinZEB1 protein, humanZinc Finger E-box-Binding Homeobox 1epithelial-mesenchymal-transitionoral canceroral epithelial celloral opportunistic pathogenPorphyromonas gingivalis

Identifiers

PMID29250491
PMCPMC5717492
OpenAlexW2772881509

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.