Evidence map›Paper›PMID 29250273›Full record

ArticleJournal of atrial fibrillation

Left Atrial Appendage characteristics in patients with Persistent Atrial Fibrillation undergoing catheter ablation (LAAPAF Study).

Enes E Gul, Usama Boles, Sohaib Haseeb, Justin Flood, Ayuish Bansal, Benedict Glover, Damian Redfearn, Chris Simpson, Hoshiar Abdollah, Adrian Baranchuk and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of atrial fibrillation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Left atrial appendage morphofunctional indices could be predictive of arrhythmia recurrence post-atrial fibrillation ablation: a meta-analysis.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2023
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Enes E GulHeart Rhythm Service, Kingston General Hospitaş, Queens University, Kingston, ON, Canada.
Usama BolesHeart Rhythm Service, Kingston General Hospitaş, Queens University, Kingston, ON, Canada.
Sohaib HaseebHeart Rhythm Service, Kingston General Hospitaş, Queens University, Kingston, ON, Canada.
Justin FloodDepartment of Diagnostic Radiology, Queens University, Kingston, ON, Canada.
Ayuish BansalHeart Rhythm Service, Kingston General Hospitaş, Queens University, Kingston, ON, Canada.
Benedict GloverHeart Rhythm Service, Kingston General Hospitaş, Queens University, Kingston, ON, Canada.
Damian RedfearnHeart Rhythm Service, Kingston General Hospitaş, Queens University, Kingston, ON, Canada.
Chris SimpsonHeart Rhythm Service, Kingston General Hospitaş, Queens University, Kingston, ON, Canada.
Hoshiar AbdollahHeart Rhythm Service, Kingston General Hospitaş, Queens University, Kingston, ON, Canada.
Adrian BaranchukHeart Rhythm Service, Kingston General Hospitaş, Queens University, Kingston, ON, Canada.
Kevin A MichaelHeart Rhythm Service, Kingston General Hospitaş, Queens University, Kingston, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite technological and scientific efforts, the recurrence rate of persistent atrial fibrillation (AF) remains high. Several studies have shown that in addition to pulmonary vein (PV) isolation other non-PV triggers, particularly left atrial appendage may be the source of initiation and maintenance of AF. There are few studies showing the role of left atrial appendage (LAA) isolation in order to obtain higher success rate in persistent AF patients.

objectiveWe analyzed the LAA volume, volume index and shape relative to the LA in patients with persistent AF undergoing AF ablation.

methodsFifty-nine consecutive patients with persistent AF who underwent catheter ablation were enrolled. Computerized tomography (CT) was performed in order to assess left atrial and PV anatomy including the LAA. Digital subtraction software (GE Advantage Workstation 4.3) was used to separate the LAA from the LA and calculate: LA volume (LAV), LA volume index (LAV/body surface area), LAA volume (LAAV), LAA volume index (LAA volume/LA volume), and LAA morphology [chicken wing (CW) or non-chicken wing (NCW)].

resultsThe mean age was 64.6 ± 9.8 years, 44 % male, and LA diameter 47.6 ± 7.8 mm. Median follow-up (FU) was 13 months. All patients had antral isolation of PVs and ablation of complex fractionation ± linear ablation (roof line/superior coronary sinus/mitral line). Among 59 patients with persistent AF, 26 (44 %) patients were diagnosed with AF recurrences. Mean LAV was 145.0 ± 45.9 ml, LAVI 68.9 ± 20.0 ml/m

conclusionThe LAA anatomical characteristics (volume/volume index and the shape) were comparable in patients with/out AF recurrence post PVI. It remains to be determined if additional LAA isolation will impact outcomes in patients with persistent AF.

Indexed as

Atrial FibrillationCardiac CTCatheter ablationLeft atrial appendage

Identifiers

PMID29250273
PMCPMC5673389

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.