Formononetin ameliorates mast cell-mediated allergic inflammation via inhibition of histamine release and production of pro-inflammatory cytokines.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

1. Efficacy and safety of Runzao Zhiyang capsule for chronic urticaria: a systematic review and meta-analysis of randomized controlled trials.Frontiers in pharmacology · 2023
   Pooled it
2. Formononetin alleviates ovarian fibrosis and inflammation via targeting SOCS3 and inhibiting TGF-Chinese herbal medicines · 2026
   Article
3. Formononetin ameliorates SP-induced urticaria in mice via suppressing TAK1/MAK signaling pathway.PloS one · 2026
   Article
4. Formononetin: pharmacological properties and therapeutic potential.Naunyn-Schmiedeberg's archives of pharmacology · 2025
   Review
5. Effect of formononetin on progressive pulmonary pathologies: multitarget mechanisms and therapeutic prospects.Frontiers in pharmacology · 2025
   Review
6. Potential mechanisms of formononetin against inflammation and oxidative stress: a review.Frontiers in pharmacology · 2024
   Review
7. Formononetin Inhibits Mast Cell Degranulation to Ameliorate Compound 48/80-Induced Pseudoallergic Reactions.Molecules (Basel, Switzerland) · 2023
   Article
8. The role of selected flavonoids from bajakah tampala (Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
   Review
9. The Protective Effect of a Functional Food Consisting ofFoods (Basel, Switzerland) · 2023
   Article
10. Network Pharmacology and Molecular Docking Study of Yupingfeng Powder in the Treatment of Allergic Diseases.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
11. Formononetin ameliorates IL‑13‑induced inflammation and mucus formation in human nasal epithelial cells by activating the SIRT1/Nrf2 signaling pathway.Molecular medicine reports · 2021
    Article
12. Flavonoids as potential phytotherapeutics to combat cytokine storm in SARS-CoV-2.Phytotherapy research : PTR · 2021
    Review
13. Formononetin ameliorates muscle atrophy by regulating myostatin-mediated PI3K/Akt/FoxO3a pathway and satellite cell function in chronic kidney disease.Journal of cellular and molecular medicine · 2021
    Article
14. Formononetin Attenuates Airway Inflammation and Oxidative Stress in Murine Allergic Asthma.Frontiers in pharmacology · 2020
    Article
15. Assessment of the antinociceptive and anti-inflammatory activities of the stem methanol extract ofPharmaceutical biology · 2019
    Article
16. The anti-inflammatory effects of formononetin and ononin on lipopolysaccharide-induced zebrafish models based on lipidomics and targeted transcriptomics.Metabolomics : Official journal of the Metabolomic Society · 2019
    Article
17. Chondroprotective Effects of a Standardized Extract (KBH-JP-040) from Kalopanax pictus, Hericium erinaceus, and Astragalus membranaceus in Experimentally Induced In Vitro and In Vivo Osteoarthritis Models.Nutrients · 2018
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

2 authors at 2 institutions in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

Indexed as