Evidence map›Paper›PMID 29250102›Full record

ArticleFrontiers in genetics2017

Analysis of the Expression of Repetitive DNA Elements in Osteosarcoma.

Xuan D Ho, Hoang G Nguyen, Le H Trinh, Ene Reimann, Ele Prans, Gea Kõks, Katre Maasalu, Van Q Le, Van H Nguyen, Nghi T N Le and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Xuan D HoDepartment of Oncology, College of Medicine and Pharmacy, Hue University, Hue, Vietnam.
Hoang G NguyenDepartment of Oncology, Hanoi Medical University, Hanoi, Vietnam.
Le H TrinhDepartment of Oncology, Hanoi Medical University, Hanoi, Vietnam.
Ene ReimannDepartment of Pathophysiology, University of Tartu, Tartu, Estonia.
Ele PransDepartment of Pathophysiology, University of Tartu, Tartu, Estonia.
Gea KõksDepartment of Pathophysiology, University of Tartu, Tartu, Estonia.
Katre MaasaluDepartment of Traumatology and Orthopedics, University of Tartu, Tartu, Estonia.
Van Q LeDepartment of Oncology, Hanoi Medical University, Hanoi, Vietnam.
Van H NguyenDepartment of Oncology, Hanoi Medical University, Hanoi, Vietnam.
Nghi T N LeDepartment of Orthopedics, College of Medicine and Pharmacy, Hue University, Hue, Vietnam.
Phuong PhungDepartment of Oncology, College of Medicine and Pharmacy, Hue University, Hue, Vietnam.
Aare MärtsonDepartment of Traumatology and Orthopedics, University of Tartu, Tartu, Estonia.
Freddy LattekiviDepartment of Pathophysiology, University of Tartu, Tartu, Estonia.
Sulev KõksDepartment of Pathophysiology, University of Tartu, Tartu, Estonia.
University of Tartu · EEHanoi Medical University · VNHue University · VNEstonian University of Life Sciences · EETartu University Hospital · EE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteosarcoma (OS) is a rare malignant bone tumor. It affects mostly young persons and has poor outcome with the present treatment. No improvement was observed since the introduction of chemotherapy. The better understanding of osteosarcoma development could indicate better management strategy. Repetitive DNA elements were found to play a role in cancer mechanism especially in epithelial tumors but not yet analyzed in osteosarcoma. We conducted the study to analyse the expression profile of repetitive elements (RE) in osteosarcoma.

Indexed as

human endogenous retrovirusosteosarcomarepetitive elementssatellitesequencetransposable elements

Identifiers

PMID29250102
PMCPMC5714928
OpenAlexW2768492030

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.