Evidence map›Paper›PMID 29250047›Full record

ReviewFrontiers in microbiology2017

The Different Faces of Rolling-Circle Replication and Its Multifunctional Initiator Proteins.

Paweł Wawrzyniak, Grażyna Płucienniczak, Dariusz Bartosik

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 85 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Whitefly transmitted begomovirus infection in plant and host response: a review.Physiology and molecular biology of plants : an international journal of functional plant biology · 2025
    Review
  6. Article
  7. Article
  8. Dietary zinc supplementation inhibits bacterial plasmid conjugationApplied and environmental microbiology · 2024
    Article
  9. Article
  10. Article
  11. An autonomous plasmid as an inovirus phage satellite.Applied and environmental microbiology · 2024
    Article
  12. De novo gene synthesis by an antiviral reverse transcriptase.bioRxiv : the preprint server for biology · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Paweł WawrzyniakDepartment of Bioengineering, Institute of Biotechnology and Antibiotics, Warsaw, Poland.
Grażyna PłucienniczakDepartment of Bioengineering, Institute of Biotechnology and Antibiotics, Warsaw, Poland.
Dariusz BartosikDepartment of Bacterial Genetics, Institute of Microbiology, Faculty of Biology, University of Warsaw, Warsaw, Poland.
Instytut Biotechnologii i Antybiotyków · PLUniversity of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Horizontal gene transfer (HGT) contributes greatly to the plasticity and evolution of prokaryotic and eukaryotic genomes. The main carriers of foreign DNA in HGT are mobile genetic elements (MGEs) that have extremely diverse genetic structures and properties. Various strategies are used for the maintenance and spread of MGEs, including (i) vegetative replication, (ii) transposition (and other types of recombination), and (iii) conjugal transfer. In many MGEs, all of these processes are dependent on rolling-circle replication (RCR). RCR is one of the most well characterized models of DNA replication. Although many studies have focused on describing its mechanism, the role of replication initiator proteins has only recently been subject to in-depth analysis, which indicates their involvement in multiple biological process associated with RCR. In this review, we present a general overview of RCR and its impact in HGT. We focus on the molecular characteristics of RCR initiator proteins belonging to the HUH and Rep_

Indexed as

conjugal transferhorizontal gene transfermobile genetic elementsmultifunctional proteinrolling-circle replicationtransposition

Identifiers

PMID29250047
PMCPMC5714925
OpenAlexW2770555788

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.