Evidence map›Paper›PMID 29249961›Full record

ArticleFrontiers in aging neuroscience2017

Gait Speed and Gait Variability Are Associated with Different Functional Brain Networks.

On-Yee Lo, Mark A Halko, Junhong Zhou, Rachel Harrison, Lewis A Lipsitz, Brad Manor

Abstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  14. Changes of neural coupling between cognitive and motor networks associated with dual-task performance in Parkinson's disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
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  16. Lower Myelin Content Is Associated With Lower Gait Speed in Cognitively Unimpaired Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

On-Yee LoInstitute for Aging Research, Hebrew SeniorLife, Boston, MA, United States.
Mark A HalkoBerenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Harvard University, Boston, MA, United States.
Junhong ZhouInstitute for Aging Research, Hebrew SeniorLife, Boston, MA, United States.
Rachel HarrisonInstitute for Aging Research, Hebrew SeniorLife, Boston, MA, United States.
Lewis A LipsitzInstitute for Aging Research, Hebrew SeniorLife, Boston, MA, United States.
Brad ManorInstitute for Aging Research, Hebrew SeniorLife, Boston, MA, United States.

Funding

Harvard Clinical and Translational Science CenterUL1TR001102 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$106.2M
Translational Researchin Aging Trainnig ProgramT32AG023480 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI LIPSITZ, LEWIS · 2004 to 2024
$7.6M
Cerebrovascular Mechanisms of Slow Gait and FallsR01AG041785 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI LIPSITZ, LEWIS · 2013 to 2017
$2.4M
Modulating brain activity to preserve gait in older adults.K01AG044543 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI MANOR, BRADLEY D. · 2014 to 2016
$373k
NCATS NIH HHS UL1 TR001102NIA NIH HHS K01 AG044543NIA NIH HHS R01 AG041785NIA NIH HHS T32 AG023480
6 · The paper itself

Abstract

Gait speed and gait variability are clinically meaningful markers of locomotor control that are suspected to be regulated by multiple supraspinal control mechanisms. The purpose of this study was to evaluate the relationships between these gait parameters and the functional connectivity of brain networks in functionally limited older adults. Twelve older adults with mild-to-moderate cognition "executive" dysfunction and relatively slow gait, yet free from neurological diseases, completed a gait assessment and a resting-state fMRI. Gait speed and variability were associated with the strength of functional connectivity of different brain networks. Those with faster gait speed had stronger functional connectivity

Indexed as

functional connectivitygaitgait speedgait variabilityresting-state fMRI

Identifiers

PMID29249961
PMCPMC5715372

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.