Evidence map›Paper›PMID 29249811›Full record

ArticleTranslational psychiatry2017

Increased decision thresholds trigger extended information gathering across the compulsivity spectrum.

Tobias U Hauser, Michael Moutoussis, NSPN Consortium, Peter Dayan, Raymond J Dolan

Abstract read
In one paragraph

Article in Translational psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Beta-Blocker Propranolol Modulates Decision Urgency During Sequential Information Gathering.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018
    Trial
  2. Article
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  7. Boosting Serotonin Increases Information Gathering by Reducing Subjective Cognitive Costs.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  8. Article
  9. Review
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  11. Dynamic Representation of the Subjective Value of Information.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  12. Article
  13. Article
  14. Selective effects of serotonin on choices to gather more information.Journal of psychopharmacology (Oxford, England) · 2021
    Article
  15. Article
  16. Article
  17. Article
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  19. Article
  20. Computational psychiatry of impulsivity and risk: how risk and time preferences interact in health and disease.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tobias U HauserWellcome Trust Centre for Neuroimaging, University College London, London, WC1N 3BG, United Kingdom. t.hauser@ucl.ac.uk.ORCID http://orcid.org/0000-0002-7997-8137
Michael MoutoussisWellcome Trust Centre for Neuroimaging, University College London, London, WC1N 3BG, United Kingdom.
NSPN Consortium
Peter DayanGatsby Computational Neuroscience Unit, University College London, London, United Kingdom.
Raymond J DolanWellcome Trust Centre for Neuroimaging, University College London, London, WC1N 3BG, United Kingdom.

Funding

Wellcome Trust 091593/Z/10/ZWellcome Trust 095844/Z/11/ZWellcome Trust 098362/Z/12/Z
6 · The paper itself

Abstract

Indecisiveness and doubt are cognitive phenotypes of compulsive disorders, including obsessive-compulsive disorder. Little is known regarding the cognitive mechanisms that drive these behaviours across a compulsivity spectrum. Here, we used a sequential information gathering task to study indecisiveness in subjects with high and low obsessive-compulsive scores. These subjects were selected from a large population-representative database, and matched for intellectual and psychiatric factors. We show that high compulsive subjects sampled more information and performed better when sampling was cost-free. When sampling was costly, both groups adapted flexibly to reduce their information gathering. Computational modelling revealed that increased information gathering behaviour could be explained by higher decision thresholds that, in turn, were driven by a delayed emergence of impatience or urgency. Our findings show that indecisiveness generalises to a compulsivity spectrum beyond frank clinical disorder, and this behaviour can be explained within a decision-theoretic framework as arising from an augmented decision threshold associated with an attenuated urgency signal.

Indexed as

Models, PsychologicalAdolescentCompulsive BehaviorDecision MakingFemaleHumansMaleObsessive-Compulsive DisorderYoung Adult

Identifiers

PMID29249811
PMCPMC5802702

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.