Evidence map›Paper›PMID 29249770›Full record

ArticleAnnals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia2018

Elevation of Serum Carcinoembryonic Antigen Concentration Caused by Everolimus-Induced Lung Injury: A Case Report.

Hiroaki Komatsu, Nobuhiro Izumi, Takuma Tsukioka, Michihito Toda, Kantaro Hara, Hikaru Miyamoto, Noritoshi Nishiyama

Open access · goldAbstract readCase Reports
In one paragraph

Article in Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Comment on "Elevation of Serum Carcinoembryonic Antigen Concentration Caused by Everolimus-Induced Lung Injury: A Case Report".Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hiroaki KomatsuDepartment of Thoracic Surgery, Osaka City University Hospital, Osaka, Osaka, Japan.
Nobuhiro IzumiDepartment of Thoracic Surgery, Osaka City University Hospital, Osaka, Osaka, Japan.
Takuma TsukiokaDepartment of Thoracic Surgery, Osaka City University Hospital, Osaka, Osaka, Japan.
Michihito TodaDepartment of Thoracic Surgery, Osaka City University Hospital, Osaka, Osaka, Japan.
Kantaro HaraDepartment of Thoracic Surgery, Osaka City University Hospital, Osaka, Osaka, Japan.
Hikaru MiyamotoDepartment of Thoracic Surgery, Osaka City University Hospital, Osaka, Osaka, Japan.
Noritoshi NishiyamaDepartment of Thoracic Surgery, Osaka City University Hospital, Osaka, Osaka, Japan.
Osaka City University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 66-year-old woman underwent right nephrectomy for treatment of renal cell carcinoma (RCC). Two years later, she underwent wedge resection of the right lung for treatment of metastatic RCC and primary adenocarcinoma of the lung. She began oral sorafenib for the remaining nodules of the left lung, which were suspected to be metastatic RCC. Two years later, the sorafenib was changed to everolimus because of slight enlargement of the left pulmonary nodules. The carcinoembryonic antigen (CEA) concentration then increased to 25.7 ng/mL, and chest computed tomography (CT) revealed ground-glass opacities (GGO) in the bilateral lungs. Everolimus-induced lung injury was suspected, and she discontinued the everolimus. Two months later, the serum CEA concentration decreased to almost within the reference range at 5.9 ng/mL, and the GGO disappeared on chest CT. In conclusion, we encountered a patient who developed an elevated serum CEA concentration caused by everolimus-induced lung injury.

Indexed as

AdenocarcinomaAdenocarcinoma of LungAgedAntineoplastic AgentsCarcinoembryonic AntigenCarcinoma, Renal CellEverolimusFemaleHumansKidney NeoplasmsLung InjuryLung NeoplasmsTomography, X-Ray ComputedUp-RegulationAntineoplastic AgentsCarcinoembryonic AntigenEverolimuscarcinoembryonic antigendrug-induced lung injuryeverolimustumor marker

Identifiers

PMID29249770
PMCPMC6033529
OpenAlexW2771394235

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.