Evidence map›Paper›PMID 29249363›Full record

ArticleTrends in parasitology2018

Tackling Hypotheticals in Helminth Genomes.

International Molecular Helminthology Annotation Network (IMHAN), IMHAN consortium authors include, Nikola Palevich, Collette Britton, Laura Kamenetzky, Makedonka Mitreva, Marina de Moraes Mourão, Sasisekhar Bennuru, Thomas Quack, Larissa Lopes Silva Scholte and 2 more

Abstract read
In one paragraph

Article in Trends in parasitology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Morphology, Molecular Characterization, and Phylogeny ofAnimals : an open access journal from MDPI · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Morphometry and Molecular Identification ofJournal of parasitology research · 2023
    Article
  7. Cestodes in the genomic era.Parasitology research · 2022
    Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Molecular Detection and Characterization ofIranian journal of parasitology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

International Molecular Helminthology Annotation Network (IMHAN)
IMHAN consortium authors include
Nikola PalevichMolecular Parasitology, Animal Science, AgResearch Ltd., Grasslands Research Centre, Palmerston North, New Zealand. Electronic address: nik.palevich@agresearch.co.nz.
Collette BrittonInstitute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow, UK.
Laura KamenetzkyInstituto de Microbiología y Parasitología Médica, Universidad de Buenos Aires Consejo Nacional de Investigaciones Científicas y Técnicas (IMPaM-UBA-CONICET), Buenos Aires, Argentina.
Makedonka MitrevaMcDonnell Genome Institute, Washington University School of Medicine, St Louis, MO, USA; Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, St Louis, MO, USA.
Marina de Moraes MourãoCentro de Pesquisas René Rachou, FIOCRUZ, Belo Horizonte, Minas Gerais, Brazil.
Sasisekhar BennuruNIAID, National Institutes of Health, Bethesda, MD, USA.
Thomas QuackBFS, Institute of Parasitology, Justus Liebig University Giessen, Germany.
Larissa Lopes Silva ScholteCentro de Pesquisas René Rachou, FIOCRUZ, Belo Horizonte, Minas Gerais, Brazil.
Rahul TyagiMcDonnell Genome Institute, Washington University School of Medicine, St Louis, MO, USA.
Barton E SlatkoMolecular Parasitology Division, New England Biolabs, Inc., Ipswich, MA, USA.

Funding

Intramural NIH HHS Z99 AI999999
6 · The paper itself

Abstract

Advancements in genome sequencing have led to the rapid accumulation of uncharacterized 'hypothetical proteins' in the public databases. Here we provide a community perspective and some best-practice approaches for the accurate functional annotation of uncharacterized genomic sequences.

Indexed as

AnimalsGenome, HelminthGenomicsHelminth ProteinsHelminthsMolecular Sequence AnnotationSequence Analysis, RNAHelminth ProteinsannotationCRISPRgenomeshelminthhypothetical genesRNAi

Identifiers

PMID29249363
PMCPMC11021132

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.