Evidence map›Paper›PMID 29249216›Full record

ArticleInfection control and hospital epidemiology2018

Pathogen Distribution and Antimicrobial Resistance Among Pediatric Healthcare-Associated Infections Reported to the National Healthcare Safety Network, 2011-2014.

Jason G Lake, Lindsey M Weiner, Aaron M Milstone, Lisa Saiman, Shelley S Magill, Isaac See

Abstract read
In one paragraph

Article in Infection control and hospital epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 1 pooled it
26.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 1 synthesis or guideline pooled it, 159 citations in OpenAlex.

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  13. High Burden of Intestinal Colonization With Antimicrobial-Resistant Bacteria in Chile: An Antibiotic Resistance in Communities and Hospitals (ARCH) Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
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  19. The Changes in Epidemiology of Imipenem-ResistantJournal of Korean medical science · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jason G Lake1Division of Healthcare Quality Promotion,Centers for Disease Control and Prevention,Atlanta,Georgia.
Lindsey M Weiner1Division of Healthcare Quality Promotion,Centers for Disease Control and Prevention,Atlanta,Georgia.
Aaron M Milstone3Department of Epidemiology,Johns Hopkins University Bloomberg School of Public Health Baltimore,Maryland.
Lisa Saiman5Department of Pediatrics,Columbia University, New York,New York.
Shelley S Magill1Division of Healthcare Quality Promotion,Centers for Disease Control and Prevention,Atlanta,Georgia.
Isaac See1Division of Healthcare Quality Promotion,Centers for Disease Control and Prevention,Atlanta,Georgia.
Centers for Disease Control and Prevention · USColumbia University · USJohns Hopkins University · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

OBJECTIVE To describe pathogen distribution and antimicrobial resistance patterns for healthcare-associated infections (HAIs) reported to the National Healthcare Safety Network (NHSN) from pediatric locations during 2011-2014. METHODS Device-associated infection data were analyzed for central line-associated bloodstream infection (CLABSI), catheter-associated urinary tract infections (CAUTI), ventilator-associated pneumonia (VAP), and surgical site infection (SSI). Pooled mean percentage resistance was calculated for a variety of pathogen-antimicrobial resistance pattern combinations and was stratified by location for device-associated infections (neonatal intensive care units [NICUs], pediatric intensive care units [PICUs], pediatric oncology and pediatric wards) and by surgery type for SSIs. RESULTS From 2011 to 2014, 1,003 hospitals reported 20,390 pediatric HAIs and 22,323 associated pathogens to the NHSN. Among all HAIs, the following pathogens accounted for more than 60% of those reported: Staphylococcus aureus (17%), coagulase-negative staphylococci (17%), Escherichia coli (11%), Klebsiella pneumoniae and/or oxytoca (9%), and Enterococcus faecalis (8%). Among device-associated infections, resistance was generally lower in NICUs than in other locations. For several pathogens, resistance was greater in pediatric wards than in PICUs. The proportion of organisms resistant to carbapenems was low overall but reached approximately 20% for Pseudomonas aeruginosa from CLABSIs and CAUTIs in some locations. Among SSIs, antimicrobial resistance patterns were similar across surgical procedure types for most pathogens. CONCLUSION This report is the first pediatric-specific description of antimicrobial resistance data reported to the NHSN. Reporting of pediatric-specific HAIs and antimicrobial resistance data will help identify priority targets for infection control and antimicrobial stewardship activities in facilities that provide care for children. Infect Control Hosp Epidemiol 2018;39:1-11.

Indexed as

Drug Resistance, BacterialAnti-Bacterial AgentsBacterial InfectionsCarbapenemsCatheter-Related InfectionsCatheters, IndwellingCenters for Disease Control and Prevention, U.S.ChildChild, PreschoolCross InfectionEnterococcus faecalisEquipment ContaminationEscherichia coliHospitalsHumansInfantAnti-Bacterial AgentsCarbapenems

Identifiers

PMID29249216
PMCPMC6643994
OpenAlexW2781132717

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.