ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2018
Medical and socioeconomic predictors of quality of life in myelomeningocele patients with shunted hydrocephalus.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- EAU-ESPU-ERN eUROGEN-ERN ITHACA-ERN ERKNet-IFSBH Guidelines on Spinal Dysraphism in Children and Adolescents: Summary of the Guideline.European urology open science · 2026Article
- Urological, Digestive and Motor Function in Children After Prenatal or Postnatal Repair of Myelomeningocele.Pediatric reports · 2025Article
- Comparison of open fetal, fetoscopic and postnatal surgical repair for open spina bifida: decision analysis.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2025Article
- Detailed analysis of hydrocephalus patterns and associated variables in patients after open fetal repair and postnatal myelomeningocele/myeloschisis closure.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- Quality of life in children operated for spina bifida; low- and middle-income country perspective.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Article
- What has changed in pediatric neurosurgical care in spina bifida? A 30-year UAB/Children's of Alabama observational overview.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Article
- Association of ethnicity and adaptive functioning with health-related quality of life in pediatric myelomeningocele.Journal of pediatric rehabilitation medicine · 2022Article
- The Quality of Life of Children with Myelomeningocele: A Cross-Sectional Preliminary Study.International journal of environmental research and public health · 2021Article
- Treatment of lumbar and intrathoracic meningocele: bioethical implications.Acta bio-medica : Atenei Parmensis · 2021Article
- Hydrocephalus-related quality of life as assessed by children and their caregivers.Journal of neurosurgery. Pediatrics · 2020Article
- Preference-based measures of health-related quality of life in congenital mobility impairment: a systematic review of validity and responsiveness.Health economics review · 2020Review
- Ambulation, lesion level, and health-related quality of life in children with myelomeningocele.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionChildren with myelomeningocele (MMC) often develop hydrocephalus, and the combination of these conditions can lead to psychosocial, cognitive, and physical health issues that decrease their health-related quality of life (HRQOL). The goal of the present study was to understand the QOL in patients with MMC and shunted hydrocephalus.
methodsData from the Toronto Hydrocephalus QOL Database was acquired between 2004 and 2009 using parent-completed questionnaires and, when appropriate, child-completed questionnaires: Hydrocephalus Outcome Questionnaire (HOQ) and the Health Utilities Index. We identified several medical and socioeconomic factors potentially relevant to the outcome measure (e.g., level of myelomeningocele, length of stay in hospital, and shunt-related hospital admissions; family functioning, income, parental education, employment status, etc.). Linear regression models were used to examine associations between potential predictor variables and HRQOL, with P < 0.05 in the multivariate model suggesting significance.
resultsThe analysis consisted of 131 patients (mean age = 12.6, SD = 3.7). The mean HUI score was 0.51, and the mean HOQ overall health score was 0.67. There was a significant association between lower age and higher HOQ social-emotional health (P = 0.03) and HUI scores (P = 0.03), lower anatomical level of myelomeningocele and higher HUI scores (P = 0.01), better family functioning and higher HOQ overall health scores (P = 0.004), and higher family income and higher HOQ overall health, physical health, and HUI scores (P = 0.001, P = 0.003, and P = 0.02, respectively).
conclusionMyelomeningocele patients with shunted hydrocephalus can have a poor health-related quality of life. Our results indicate a strong association of income and family functioning on quality of life, along with younger age and lower level of myelomeningocele.
Indexed as
Identifiers
29249073What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.