Evidence map›Paper›PMID 29248987›Full record

ArticleInternational journal of clinical pharmacy2018

Healthcare professionals' agreement on clinical relevance of drug-related problems among elderly patients.

Christine Flagstad Bech, Tine Frederiksen, Christine Tilsted Villesen, Jette Højsted, Per Rotbøll Nielsen, Lene Juel Kjeldsen, Lotte Stig Nørgaard, Lona Louring Christrup

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Article in International journal of clinical pharmacy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Christine Flagstad BechDepartment of Drug Design and Pharmacology, University of Copenhagen, 2 Universitetsparken, Copenhagen, Denmark.
Tine FrederiksenDepartment of Drug Design and Pharmacology, University of Copenhagen, 2 Universitetsparken, Copenhagen, Denmark.
Christine Tilsted VillesenDepartment of Drug Design and Pharmacology, University of Copenhagen, 2 Universitetsparken, Copenhagen, Denmark.
Jette HøjstedMultidisciplinary Pain Centre, Copenhagen University Hospital, 9. Blegdamsvej, Copenhagen, Denmark.
Per Rotbøll NielsenMultidisciplinary Pain Centre, Copenhagen University Hospital, 9. Blegdamsvej, Copenhagen, Denmark.
Lene Juel KjeldsenAmgros I/S, Dampfaergevej 22, Copenhagen, Denmark.
Lotte Stig NørgaardDepartment of Pharmacy, University of Copenhagen, 2 Universitetsparken, Copenhagen, Denmark.
Lona Louring ChristrupDepartment of Drug Design and Pharmacology, University of Copenhagen, 2 Universitetsparken, Copenhagen, Denmark. llc@sund.ku.dk.ORCID http://orcid.org/0000-0002-4128-7373

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Disagreement among healthcare professionals on the clinical relevance of drug-related problems can lead to suboptimal treatment and increased healthcare costs. Elderly patients with chronic non-cancer pain and comorbidity are at increased risk of drug related problems compared to other patient groups due to complex medication regimes and transition of care. Objective To investigate the agreement among healthcare professionals on their classification of clinical relevance of drug-related problems in elderly patients with chronic non-cancer pain and comorbidity. Setting Multidisciplinary Pain Centre, Rigshospitalet, Copenhagen, Denmark. Method A pharmacist performed medication review on elderly patients with chronic non-cancer pain and comorbidity, identified their drug-related problems and classified these problems in accordance with an existing categorization system. A five-member clinical panel rated the drug-related problems' clinical relevance in accordance with a five-level rating scale, and their agreement was compared using Fleiss' κ. Main outcome measure Healthcare professionals' agreement on clinical relevance of drug related problems, using Fleiss' κ. Results Thirty patients were included in the study. A total of 162 drug related problems were identified, out of which 54% were of lower clinical relevance (level 0-2) and 46% of higher clinical relevance (level 3-4). Only slight agreement (κ = 0.12) was found between the panellists' classifications of clinical relevance using a five-level rating scale. Conclusion The clinical pharmacist identified drug related problems of lower and higher clinical relevance. Poor overall agreement on the severity of the drug related problems was found among the panelists.

Indexed as

PolypharmacyAgedAged, 80 and overDrug-Related Side Effects and Adverse ReactionsFemaleHealth PersonnelHumansMaleMedication ReconciliationPatient Care TeamPatient TransferPharmacistsProspective StudiesCare transitionClinical relevanceDRP classificationDrug-related problemsInter-rater agreementMedication review

Identifiers

PMID29248987

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.