SynthesisSleep & breathing = Schlaf & Atmung2018
A meta-analysis of obstructive sleep apnea in patients with cerebrovascular disease.
Synthesis in Sleep & breathing = Schlaf & Atmung, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- An umbrella review of systematic reviews and meta-analyses of observational investigations of obstructive sleep apnea and health outcomes.Sleep & breathing = Schlaf & Atmung · 2022Pooled it
- Meta-Analysis of the Relationship between the Prognosis of Acute Cerebral Infarction Intravenous Lysis and Cerebral Microbleeds Based on Intelligent Medical Care.Contrast media & molecular imaging · 2022Pooled it
- Comparing the effects of supplemental oxygen therapy and continuous positive airway pressure on patients with obstructive sleep apnea: a meta-analysis of randomized controlled trials.Sleep & breathing = Schlaf & Atmung · 2021Pooled it
- Sleep architecture characteristics in patients with acute ischemic stroke.Scientific reports · 2025Article
- Article
- Study on the circadian rhythm and sleep state characteristics of patients with acute cerebral infarction accompanied by sleep-breathing disorders.Sleep and biological rhythms · 2024Article
- Transforming the cardiometabolic disease landscape: Multimodal AI-powered approaches in prevention and management.Cell metabolism · 2024Review
- 2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association.Circulation · 2024Review
- International Consensus Statement on Obstructive Sleep Apnea.International forum of allergy & rhinology · 2023Review
- Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association.Circulation · 2023Review
- Causal Relations Between Obstructive Sleep Apnea and Stroke: A Mendelian Randomization Study.Nature and science of sleep · 2023Article
- Self-reported symptoms of sleep-disordered breathing and risk of cardiovascular diseases: Observational and Mendelian randomization findings.Journal of sleep research · 2022Article
- Posttraumatic stress disorder (PTSD), sleep, and cardiovascular disease risk: A mechanism-focused narrative review.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2022Review
- Sleep Apnea and Serum Serotonin Level Pre- and Post-PAP Therapy: A Preliminary Study.Neurology and therapy · 2021Article
- Heart Disease and Stroke Statistics-2021 Update: A Report From the American Heart Association.Circulation · 2021Article
- The "Neural Shift" of Sleep Quality and Cognitive Aging: A Resting-State MEG Study of Transient Neural Dynamics.Frontiers in aging neuroscience · 2021Article
- Sleep disturbances and the speed of multimorbidity development in old age: results from a longitudinal population-based study.BMC medicine · 2020Article
- SAS CARE 2 - a randomized study of CPAP in patients with obstructive sleep disordered breathing following ischemic stroke or transient ischemic attack.Sleep medicine: X · 2020Article
- SAS Care 1: sleep-disordered breathing in acute stroke an transient ischaemic attack - prevalence, evolution and association with functional outcome at 3 months, a prospective observational polysomnography study.ERJ open research · 2020Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is increasing evidence that there is a direct relationship between obstructive sleep apnea (OSA) and cerebrovascular (CV) disease. This meta-analysis includes prospective cohorts and cross-sectional studies. It determines the prevalence of OSA among patients with CV disease and also looks for the risk o f cerebrovascular events among patients with OSA.
methodWe conducted a computerized literature search in the databases of Medline, Embase, Wanfang, CNKI, Wiley Online Library, and CINAHL (date till April 2017). The random effects model was used to pool the hazard ratio (HR) and effect sizes (ES). Heterogeneity, subgroup, sensitivity analyses, and publication bias were performed.
resultFifty-eight studies involving 3 million patients/participants were included. The pooled HR of 15 prospective cohort studies indicated a significant association between OSA and the risk of CV disease after adjustment confounding factors (HR 1.94; 95% CI 1.31-2.89; P = 0.001), and OSA is present in up to 58.8% of patients with CV disease after pooling the remaining 43 studies.
conclusionsOSA is very common in patients with CV disease. Similarly, patients with OSA are prone to have CV disease.
Indexed as
Identifiers
29248975What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.