ArticleNeuroImage2018
Multiple time courses of somatosensory responses in human cortex.
Article in NeuroImage, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Functional architecture of the human insula.Nature · 2026Article
- Functional Architecture of the Human Insula Revealed by Causal Intracranial Mapping.Research square · 2026Article
- Extracting robust single-trial somatosensory evoked potentials for non-invasive brain computer interfaces.Journal of neural engineering · 2025Article
- Task Relevance Modulates Somatosensory Awareness Depending on Stimulus Intensity.The European journal of neuroscience · 2025Article
- Simultaneously Acquired Magnetoencephalography and Diffuse Optical Tomography Data Reveals Correlated Somatosensory Activity.Human brain mapping · 2025Article
- Frequency dependence of cortical somatosensory evoked response to peripheral nerve stimulation with controlled afferent excitation.Journal of neural engineering · 2025Article
- Gating of Neuroplasticity: Effects and Mechanisms of Acute Aerobic Exercise as a Brain Stimulation for the Sensorimotor Cortex.Advances in neurobiology · 2025Review
- Anatomo-functional basis of emotional and motor resonance elicited by facial expressions.Brain : a journal of neurology · 2024Article
- Long-latency gamma modulation after median nerve stimulation delineates the central sulcus and contrasts the states of consciousness.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2023Article
- The web of laughter: frontal and limbic projections of the anterior cingulate cortex revealed by cortico-cortical evoked potential from sites eliciting laughter.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Tonic somatosensory responses and deficits of tactile awareness converge in the parietal operculum.Brain : a journal of neurology · 2021Article
- Neural surprise in somatosensory Bayesian learning.PLoS computational biology · 2021Article
- Why brain-controlled neuroprosthetics matter: mechanisms underlying electrical stimulation of muscles and nerves in rehabilitation.Biomedical engineering online · 2020Review
- Action execution and action observation elicit mirror responses with the same temporal profile in human SII.Communications biology · 2020Article
- La Recherche du Temps Perdu: Timing in Somatosensation. Commentary: Somatosensation in the Brain: A Theoretical Re-evaluation and a New Model.Frontiers in systems neuroscience · 2020Article
- Suppression of Somatosensory Evoked Cortical Responses by Noxious Stimuli.Brain topography · 2019Article
- System neuroscience: Past, present, and future.CNS neuroscience & therapeutics · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Here we show how anatomical and functional data recorded from patients undergoing stereo-EEG can be used to decompose the cortical processing following nerve stimulation in different stages characterized by specific topography and time course. Tibial, median and trigeminal nerves were stimulated in 96 patients, and the increase in gamma power was evaluated over 11878 cortical sites. All three nerve datasets exhibited similar clusters of time courses: phasic, delayed/prolonged and tonic, which differed in topography, temporal organization and degree of spatial overlap. Strong phasic responses of the three nerves followed the classical somatotopic organization of SI, with no overlap in either time or space. Delayed responses presented overlaps between pairs of body parts in both time and space, and were confined to the dorsal motor cortices. Finally, tonic responses occurred in the perisylvian region including posterior insular cortex and were evoked by the stimulation of all three nerves, lacking any spatial and temporal specificity. These data indicate that the somatosensory processing following nerve stimulation is a multi-stage hierarchical process common to all three nerves, with the different stages likely subserving different functions. While phasic responses represent the neural basis of tactile perception, multi-nerve tonic responses may represent the neural signature of processes sustaining the capacity to become aware of tactile stimuli.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.