Evidence map›Paper›PMID 29247790›Full record

ArticleExperimental gerontology2018

Age-related reduction in single muscle fiber calcium sensitivity is associated with decreased muscle power in men and women.

Chad R Straight, Philip A Ades, Michael J Toth, Mark S Miller

Open access · greenAbstract readComparative Study
In one paragraph

Article in Experimental gerontology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Effects of acidosis and inorganic phosphate on CaAmerican journal of physiology. Cell physiology · 2026
    Article
  5. Review
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  8. Review
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  10. Review
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  12. Article
  13. Super-relaxed state of myosin in human skeletal muscle is fiber-type dependent.American journal of physiology. Cell physiology · 2020
    Article
  14. Influenza Infection has Fiber Type-Specific Effects on Cellular and Molecular Skeletal Muscle Function in Aged Mice.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020
    Article
  15. CaAmerican journal of physiology. Cell physiology · 2020
    Article
  16. Single-muscle fiber contractile properties in lifelong aerobic exercising women.Journal of applied physiology (Bethesda, Md. : 1985) · 2019
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Chad R StraightDepartment of Kinesiology, University of Massachusetts Amherst, 140E Totman Building, 30 Eastman Lane, Amherst, MA 01003, USA. Electronic address: cstraight@umass.edu.
Philip A AdesDepartment of Medicine, University of Vermont, Main Campus, McClure, Level 1, 111 Colchester Avenue, Burlington, VT 05401, USA. Electronic address: philip.ades@uvmhealth.org.
Michael J TothDepartments of Medicine, Molecular Physiology and Biophysics, and Orthopedics and Rehabilitation, University of Vermont, Health Science Research Facility 126B, 149 Beaumont Avenue, Burlington, VT 05405, USA. Electronic address: michael.toth@uvm.edu.
Mark S MillerDepartment of Molecular Physiology and Biophysics, University of Vermont, Health Science Research Facility 127, 149 Beaumont Avenue, Burlington, VT 05405, USA. Electronic address: markmiller@umass.edu.
University of Vermont · USUniversity of Massachusetts Amherst · US

Funding

Muscle disuse and contractile dysfunction in the elderlyR01AG033547 · NIA · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI TOTH, MICHAEL J · 2010 to 2014
$1.9M
Single Skeletal Muscle Fiber Mechanics and Myosin Kinetics in Human AgingK01AG031303 · NIA · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI MILLER, MARK STUART · 2008 to 2012
$611k
NIA NIH HHS K01 AG031303NIA NIH HHS R01 AG033547
6 · The paper itself

Abstract

Age-related declines in human skeletal muscle performance may be caused, in part, by decreased responsivity of muscle fibers to calcium (Ca

Indexed as

Calcium SignalingMuscle ContractionMuscle StrengthAdultAgedAge FactorsAgingCalciumFemaleHumansMaleMuscle Fibers, Fast-TwitchMuscle Fibers, Slow-TwitchMyosin Heavy ChainsQuadriceps MuscleYoung AdultCalciumMyosin Heavy ChainsHumanMuscle functionMyosin heavy chain isoformsSpecific force

Identifiers

PMID29247790
PMCPMC6411279
OpenAlexW2772803303

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.