Evidence map›Paper›PMID 29247550›Full record

ArticleJournal of pineal research2018

Melatonin prevents hypochlorous acid-mediated cyanocobalamin destruction and cyanogen chloride generation.

Roohi Jeelani, Dhiman Maitra, Charalampos Chatzicharalampous, Syed Najeemuddin, Robert T Morris, Husam M Abu-Soud

Abstract read
In one paragraph

Article in Journal of pineal research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Roohi JeelaniDepartment of Obstetrics and Gynecology, C. S. Mott Center for Human Growth and Development, Wayne State University School of Medicine, Detroit, MI, USA.
Dhiman MaitraDepartment of Obstetrics and Gynecology, C. S. Mott Center for Human Growth and Development, Wayne State University School of Medicine, Detroit, MI, USA.
Charalampos ChatzicharalampousDepartment of Obstetrics and Gynecology, C. S. Mott Center for Human Growth and Development, Wayne State University School of Medicine, Detroit, MI, USA.
Syed NajeemuddinDepartment of Obstetrics and Gynecology, C. S. Mott Center for Human Growth and Development, Wayne State University School of Medicine, Detroit, MI, USA.
Robert T MorrisDivision of Gynecologic Oncology, Department of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI, USA.
Husam M Abu-SoudDepartment of Obstetrics and Gynecology, C. S. Mott Center for Human Growth and Development, Wayne State University School of Medicine, Detroit, MI, USA.ORCID http://orcid.org/0000-0003-0939-4256
Wayne State University · US

Funding

Regulation of Myeloperoxidase Catalysis by Nitric OxideR01HL066367 · NHLBI · WAYNE STATE UNIVERSITY · PI ABU-SOUD, HUSAM M · 2001 to 2004
$1.2M
NHLBI NIH HHS R01 HL066367
6 · The paper itself

Abstract

Hypochlorous acid (HOCl) is a potent cytotoxic oxidant generated by the enzyme myeloperoxidase (MPO) in the presence of hydrogen peroxide (H

Indexed as

AnimalsAntioxidantsChromatography, High Pressure LiquidCyanidesHumansHypochlorous AcidIn Vitro TechniquesKineticsMelatoninSpectrophotometryVitamin B 12AntioxidantsCyanidescyanogen chlorideHypochlorous AcidMelatoninVitamin B 12circadian rhythmcyanocobalaminhypochlorous acidmammalian peroxidasesmelatoninvitamin B12

Identifiers

PMID29247550
PMCPMC5843513
OpenAlexW2775811271

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.