ArticleEJNMMI physics2017
Monte Carlo-based quantitative pinhole SPECT reconstruction using a ray-tracing back-projector.
Article in EJNMMI physics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Fast and accurate iterative reconstruction using a volume integral model with look-up tables for pinhole SPECT.Radiological physics and technology · 2026Article
- Monte Carlo methods for medical imaging research.Biomedical engineering letters · 2024Review
- Verification of phantom accuracy using a Monte Carlo simulation: bone scintigraphy chest phantom.Radiological physics and technology · 2021Article
- The clinical utilities of multi-pinhole single photon emission computed tomography.Quantitative imaging in medicine and surgery · 2020Review
- Virtual clinical trials in medical imaging: a review.Journal of medical imaging (Bellingham, Wash.) · 2020Review
- Counter examples for unmatched projector/backprojector in an iterative algorithm.Chinese journal of academic radiology · 2019Article
- Patient-specific image-based bone marrow dosimetry in Lu-177-[DOTAEJNMMI research · 2018Article
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Authors and funding
3 authors.
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Abstract
backgroundMonte Carlo simulations provide accurate models of nuclear medicine imaging systems as they can properly account for the full physics of photon transport. The accuracy of the model included in the maximum-likelihood-expectation-maximization (ML-EM) reconstruction limits the overall accuracy of the reconstruction results. In this paper, we present a Monte Carlo-based ML-EM reconstruction method for pinhole single-photon emission computed tomography (SPECT) that has been incorporated into the SIMIND Monte Carlo program. The Monte Carlo-based model, which accounts for all of the physical and geometrical characteristics of the camera system, is used in the forward-projection step of the reconstruction, while a simpler model based on ray-tracing is used for back-projection. The aim of this work was to investigate the quantitative accuracy of this combination of forward- and back-projectors in the clinical pinhole camera GE Discovery NM 530c.
resultsThe total activity was estimated in
conclusionsWe developed a Monte Carlo-based reconstruction method for pinhole SPECT and evaluated it using phantom measurements. The combination of a Monte Carlo-based forward-projector and a simplified analytical ray-tracing back-projector produced quantitative images of acceptable image quality. No explicit calibration is necessary in this method since the forward-projector model maintains a relationship between the number of counts and activity.
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