Evidence map›Paper›PMID 29247204›Full record

ArticleScientific reports2017

Antibacterial activity of ceramide and ceramide analogs against pathogenic Neisseria.

Jérôme Becam, Tim Walter, Anne Burgert, Jan Schlegel, Markus Sauer, Jürgen Seibel, Alexandra Schubert-Unkmeir

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 48 citations in OpenAlex.

  1. Multi-omics uncovers the critical role of ceramide-mediatedJournal of pharmaceutical analysis · 2026
    Article
  2. Article
  3. Review
  4. Extracellular vesicles ofGut microbes · 2025
    Article
  5. Sphingosine-mediated death ofInfection and immunity · 2025
    Article
  6. Article
  7. Review
  8. Antibacterial Effects ofMolecules (Basel, Switzerland) · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Antimicrobial Tear Lipids in the Ocular Surface Defense.Frontiers in cellular and infection microbiology · 2022
    Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Characterization of Endophytic Fungi,BioMed research international · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jérôme BecamInstitute of Hygiene and Microbiology, Julius-Maximilian University Wuerzburg, Wuerzburg, Germany.
Tim WalterInstitute for Organic Chemistry, Julius-Maximilian University Wuerzburg, Wuerzburg, Germany.ORCID 0000-0002-5961-8927
Anne BurgertDepartment of Biotechnology and Biophysics, Julius-Maximilian University Wuerzburg, Wuerzburg, Germany.
Jan SchlegelDepartment of Biotechnology and Biophysics, Julius-Maximilian University Wuerzburg, Wuerzburg, Germany.ORCID 0000-0003-3159-8079
Markus SauerDepartment of Biotechnology and Biophysics, Julius-Maximilian University Wuerzburg, Wuerzburg, Germany.
Jürgen SeibelInstitute for Organic Chemistry, Julius-Maximilian University Wuerzburg, Wuerzburg, Germany.
Alexandra Schubert-UnkmeirInstitute of Hygiene and Microbiology, Julius-Maximilian University Wuerzburg, Wuerzburg, Germany. aunkmeir@hygiene.uni-wuerzburg.de.
University of Würzburg · DEInstitute of Medical Microbiology and Hygiene · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Certain fatty acids and sphingoid bases found at mucosal surfaces are known to have antibacterial activity and are thought to play a more direct role in innate immunity against bacterial infections. Herein, we analysed the antibacterial activity of sphingolipids, including the sphingoid base sphingosine as well as short-chain C

Indexed as

Anti-Bacterial AgentsBiological TransportCell Line, TumorCell MembraneCeramidesFlow CytometryHEK293 CellsHep G2 CellsHumansMicrobial Sensitivity TestsMicroscopy, ConfocalNeisseria gonorrhoeaeNeisseria meningitidisSphingolipidsSphingosineStaphylococcus aureusAnti-Bacterial AgentsCeramidesSphingolipidsSphingosine

Identifiers

PMID29247204
PMCPMC5732201
OpenAlexW2773040489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.