Evidence map›Paper›PMID 29247092›Full record

ArticleBMJ open2017

Factors associated with high levels of glycated haemoglobin in patients with type 1 diabetes: a multicentre study in Brazil.

Carine Sousa Andrade, Guilherme Sousa Ribeiro, Carlos Antonio Souza Teles Santos, Raimundo Celestino Silva Neves, Edson Duarte Moreira

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
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  9. NAFLD in type 1 diabetes: overrated or underappreciated?Therapeutic advances in endocrinology and metabolism · 2021
    Review
  10. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Carine Sousa AndradeGonçalo Moniz Institute, Oswaldo Cruz Foundation, Salvador, Brazil.
Guilherme Sousa RibeiroGonçalo Moniz Institute, Oswaldo Cruz Foundation, Salvador, Brazil.
Carlos Antonio Souza Teles SantosGonçalo Moniz Institute, Oswaldo Cruz Foundation, Salvador, Brazil.
Raimundo Celestino Silva NevesGonçalo Moniz Institute, Oswaldo Cruz Foundation, Salvador, Brazil.
Edson Duarte MoreiraGonçalo Moniz Institute, Oswaldo Cruz Foundation, Salvador, Brazil.
Fundação Oswaldo Cruz · BRUniversidade Federal da Bahia · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveLong-term complications of type 1 diabetes mellitus (DM1) can be prevented with adequate glycaemic control. However, high levels of glycated haemoglobin (HbA1c) occur in 60%-90% of the patients with DM1. Thus, we aimed to investigate the role of sociodemographic, behavioural and clinical factors on the HbA1c levels of patients with DM1 in Brazil. DESIGN, SETTING AND

participantsA cross-sectional study was conducted in ambulatory patients with DM1 aged ≥18 years from 10 Brazilian cities. Sociodemographic, behavioural and clinical data were obtained through interviews.

main outcome measuresHbA1c level was measured by liquid chromatography. Hierarchical multiple variable linear regression models were used to identify factors correlated with high levels of HbA1c.

resultsOf 979 patients with DM1, 63.8% were women, and the mean age was 40 (SD 14.6) years. The mean HbA1c level was 9.4% (SD 2.2%), and 89.6% of the patients had HbA1c ≥7.0%. Factors independently correlated with increased HbA1c levels included: lower education, non-participation in diabetes classes/lecture during the year before, having a self-perception of poor adherence to diet and insulin, not having private medical care and not measuring the HbA1c levels in the prior year. Of note, poor adherence to diet and insulin were the independent factors most strongly associated with high levels of HbA1c (mean increment in HbA1c levels of 0.88% and 1.25%, respectively).

conclusionPoor glycaemic control, which is common among Brazilian patients with DM1, is associated with lower education, self-perception of insufficient adherence to diet and insulin and inadequate monitoring of HbA1c levels. Specific actions, particularly those targeting improving adherence to diet and insulin, may contribute to successful management of patients with DM1.

Indexed as

Educational StatusPatient ComplianceAdolescentAdultBrazilCross-Sectional StudiesDiabetes Mellitus, Type 1Diet TherapyFemaleGlycated HemoglobinHumansHypoglycemic AgentsInsulinLinear ModelsMaleMiddle AgedGlycated HemoglobinHypoglycemic AgentsInsulinepidemiologyGlycaemic controlglycated Haemoglobintype 1 diabetes

Identifiers

PMID29247092
PMCPMC5736030
OpenAlexW2774639539

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.