Evidence map›Paper›PMID 29247089›Full record

Observational studyBMJ open2017

Study protocol for

Apurv Soni, Sunil Karna, Harshil Patel, Nisha Fahey, Shyamsundar Raithatha, Anna Handorf, John Bostrom, Syed Bashar, Kandarp Talati, Ravi Shah and 7 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Early Detection of Atrial Fibrillation Based on ECG Signals.Bioengineering (Basel, Switzerland) · 2020
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 2 countries.

Apurv SoniQuantitative Health Sciences, University of Massachusetts Medical School, Worcester, Massachusetts, USA.ORCID http://orcid.org/0000-0001-5049-3657
Sunil KarnaCardiovascular Medicine, Pramukhswami Medical College, Karamsad, Gujarat, India.
Harshil PatelCentral Research Services, Pramukhswami Medical College, Karamsad, Gujarat, India.
Nisha FaheyPediatrics, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Shyamsundar RaithathaCommunity Extension, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Anna HandorfSchool of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
John BostromSchool of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Syed BasharBiomedical Engineering, University of Connecticut, Storrs, Connecticut, USA.
Kandarp TalatiCentral Research Services, Pramukhswami Medical College, Karamsad, Gujarat, India.
Ravi ShahPediatrics, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Robert J GoldbergQuantitative Health Sciences, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Sunil ThanviCardiovascular Medicine, Pramukhswami Medical College, Karamsad, Gujarat, India.
Ajay Gajanan PhatakCentral Research Services, Pramukhswami Medical College, Karamsad, Gujarat, India.ORCID http://orcid.org/0000-0002-8876-8684
Jeroan J AllisonQuantitative Health Sciences, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Ki ChonBiomedical Engineering, University of Connecticut, Storrs, Connecticut, USA.
Somashekhar Marutirao NimbalkarCentral Research Services, Pramukhswami Medical College, Karamsad, Gujarat, India.
David D McManusQuantitative Health Sciences, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
University of Massachusetts Chan Medical School · USPramukhswami Medical College · INUniversity of Connecticut · US

Funding

University of Massachusetts Center for Clinical Science and Translational SupplementUL1TR001453 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LUZURIAGA, KATHERINE F · 2015 to 2024
$39.0M
UMass Center for Health Equity Intervention ResearchP60MD006912 · NIMHD · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LEMON, STEPHENIE C. · 2012 to 2016
$6.8M
University of Massachusetts Center for Clinical and Translational ScienceTL1TR001454 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LEWIS, BRIAN C · 2015 to 2024
$3.6M
Systematic Assessment of Geriatric Elements in Atrial Fibrillation (SAGE-AF)R01HL126911 · NHLBI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI MCMANUS, DAVID D., SACZYNSKI, JANE STEELE · 2016 to 2019
$3.2M
University of Massachusetts Center for Clinical and Translational ScienceKL2RR031981 · NCRR · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SULLIVAN, JOHN LEWIS · 2010 to 2011
$1.2M
Extracellular RNAs: Biomarkers for Cardiovascular Risk and DiseaseUH2TR000921 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI FREEDMAN, JANE E · 2013 to 2014
$1.0M
Arrhythmia Detection Using a Smart PhoneR15HL121761 · NHLBI · WORCESTER POLYTECHNIC INSTITUTE · PI CHONG, JO WOON · 2014 to 2014
$389k
Trends, Predictors, and Consequences of Child UndernutritionF30HD091975 · NICHD · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SONI, APURV · 2017 to 2020
$142k
NCATS NIH HHS TL1 TR001454NCATS NIH HHS UH2 TR000921NCATS NIH HHS UL1 TR001453NCRR NIH HHS KL2 RR031981NHLBI NIH HHS R01 HL126911NHLBI NIH HHS R15 HL121761NICHD NIH HHS F30 HD091975NIMHD NIH HHS P60 MD006912
6 · The paper itself

Abstract

introductionAtrial fibrillation (AF), the world's most common arrhythmia, often goes undetected and untreated in low-resource communities, including India, where AF epidemiology is undefined. AF is an important risk factor for stroke, which plagues an estimated 1.6 million Indians annually. As such, early detection of AF and management of high-risk patients is critically important to decrease stroke burden in individuals with AF. This study aims to describe the epidemiology of AF in Anand District, Gujarat, India, characterise the clinical profile of individuals who are diagnosed with AF and determine the performance of two mobile technologies for community-based AF screening.

methodsThis observational study builds on findings from a previous feasibility study and leverages two novel technologies as well as an existing community health programme to perform door-to-door AF screening for 2000 people from 60 villages of Anand District, Gujarat, India using local health workers. A single-lead ECG and a pulse-based application is used to screen each individual for AF three times over a period of 5 days. Participants with suspected arrhythmias are followed up by study cardiologist who makes final diagnoses. Participants diagnosed with AF are initiated on treatment based on current anticoagulation guidelines and clinical reasoning. ANALYTICAL PLAN: Age-stratified and sex-stratified prevalence of AF in the Anand District will be calculated for sample and estimated for Anand distribution using survey design weights. Sociodemographic and clinical factors associated with AF will be evaluated using multivariable regression methods. Performance of each mobile technology in detecting AF will be evaluated using a 12-lead ECG interpretation as the gold standard. ETHICS AND DISSEMINATION: This protocol was approved separately by the Institutional Review Board of University of Massachusetts Medical School and the Human Research Ethics Committee at Charutar Arogya Mandal. The findings of this study will be disseminated through peer-reviewed journals and scientific conferences.

Indexed as

SmartphoneAgedAged, 80 and overAtrial FibrillationCross-Sectional StudiesElectrocardiographyFemaleHumansIndiaMaleMass ScreeningMiddle AgedMonitoring, PhysiologicMultivariate AnalysisReferral and ConsultationRegression Analysiscardiac epidemiologypublic healthvalvular heart disease

Identifiers

PMID29247089
PMCPMC5736031
OpenAlexW2773827943

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.