Evidence map›Paper›PMID 29247012›Full record

ArticleGenetics2018

Loss of

Morgan M Brady, Susan McMahan, Jeff Sekelsky

Abstract read
In one paragraph

Article in Genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Centromere-Proximal Suppression of Meiotic Crossovers inbioRxiv : the preprint server for biology · 2023
    Article
  9. Article
  10. Article
  11. Meiotic Crossover Patterning.Frontiers in cell and developmental biology · 2021
    Review
  12. Review
  13. Phospho-Regulation of Meiotic Prophase.Frontiers in cell and developmental biology · 2021
    Review
  14. Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Morgan M BradyCurriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, North Carolina 27599.
Susan McMahanDepartment of Biology, University of North Carolina, Chapel Hill, North Carolina 27599.
Jeff SekelskyCurriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, North Carolina 27599 sekelsky@unc.edu.ORCID 0000-0002-4424-677X

Funding

Mechanisms of Meiotic and Mitotic RecombinationR35GM118127 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JEFF J. SEKELSKY · 2016 to 2026
$6.0M
NRSA IN GENETICST32GM007092 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SEKELSKY, JEFF J. · 1985 to 2019
$5.9M
NIGMS NIH HHS R35 GM118127NIGMS NIH HHS T32 GM007092
6 · The paper itself

Abstract

Meiotic crossovers must be properly patterned to ensure accurate disjunction of homologous chromosomes during meiosis I. Disruption of the spatial distribution of crossovers can lead to nondisjunction, aneuploidy, gamete dysfunction, miscarriage, or birth defects. One of the earliest identified genes involved in proper crossover patterning is

Indexed as

Crossing Over, GeneticAllelesAnimalsCell Cycle ProteinsCentromereDrosophilaDrosophila ProteinsGene ExpressionGenotypeMeiosisMutationProtein Serine-Threonine KinasesRecombination, GeneticCell Cycle ProteinsDrosophila ProteinsMei-41 protein, DrosophilaProtein Serine-Threonine KinasesATR kinasecentromere effectDrosophilainterferencemeiotic recombination

Identifiers

PMID29247012
PMCPMC5788523

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.