Evidence map›Paper›PMID 29246869›Full record

ReviewMitochondrion2018

The essential role of mitochondrial dynamics in antiviral immunity.

Seong-Jun Kim, Dae-Gyun Ahn, Gulam H Syed, Aleem Siddiqui

Open access · hybridAbstract readReview
In one paragraph

Review in Mitochondrion, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it, 104 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Antioxidants and Calcium Modulators Preclude in Vitro Hepatitis B Virus-Induced Mitochondrial Damage.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023
    Article
  15. Large yellow croaker (Marine life science & technology · 2023
    Article
  16. Article
  17. Article
  18. Review
  19. Host mitochondria: more than an organelle in SARS-CoV-2 infection.Frontiers in cellular and infection microbiology · 2023
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Seong-Jun KimCenter for Convergent Research of Emerging Virus Infection, Korea Research Institute of Chemical Technology, Yuseong, Daejeon 34114, South Korea.
Dae-Gyun AhnCenter for Convergent Research of Emerging Virus Infection, Korea Research Institute of Chemical Technology, Yuseong, Daejeon 34114, South Korea.
Gulam H SyedInstitute of Life Sciences, Bhubaneswar, Odisha 751023, India.
Aleem SiddiquiDivision of Infectious Diseases, Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: asiddiqui@ucsd.edu.
Korea Research Institute of Chemical Technology · KRInstitute of Life Sciences · INUniversity of California San Diego · US

Funding

Viral Hepatitis C and Lipid HomeostasisR01DK077704 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SIDDIQUI, ALEEM · 2008 to 2017
$3.0M
Role of Lipids in Hepatitis C Virus MaturationR01AI085087 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SIDDIQUI, ALEEM · 2010 to 2018
$2.9M
Mechanisms of HBV-Induced Innate ImmunityR01AI125350 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SIDDIQUI, ALEEM · 2017 to 2021
$1.9M
HBV INDUCED LIVER PATHOGENESISR01CA064415 · NCI · UNIVERSITY OF COLORADO DENVER · PI SIDDIQUI, ALEEM · 1996 to 2005
$1.5M
DBT-Wellcome Trust India Alliance IA/I/15/1/501826NCI NIH HHS R01 CA064415NIAID NIH HHS R01 AI085087NIAID NIH HHS R01 AI125350NIDDK NIH HHS R01 DK077704
6 · The paper itself

Abstract

Viruses alter cellular physiology and function to establish cellular environment conducive for viral proliferation. Viral immune evasion is an essential aspect of viral persistence and proliferation. The multifaceted mitochondria play a central role in many cellular events such as metabolism, bioenergetics, cell death, and innate immune signaling. Recent findings accentuate that viruses regulate mitochondrial function and dynamics to facilitate viral proliferation. In this review, we will discuss how viruses exploit mitochondrial dynamics to modulate mitochondria-mediated antiviral innate immune response during infection. This review will provide new insight to understanding the virus-mediated alteration of mitochondrial dynamics and functions to perturb host antiviral immune signaling.

Indexed as

Mitochondrial DynamicsAnimalsHost-Pathogen InteractionsHumansImmune EvasionImmunity, InnateMitochondriaSignal TransductionViruses

Identifiers

PMID29246869
PMCPMC5988924
OpenAlexW2773560724

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.