Evidence map›Paper›PMID 29246819›Full record

Trial reportContraception2018

Discordance between self-reported contraceptive use and detection of exogenous hormones among Malawian women enrolling in a randomized clinical trial.

Anuli N Nwaohiri, Jennifer H Tang, Frank Stanczyk, Lameck Chinula, Stacey Hurst, Nicole L Davis, Gerald Tegha, Lisa Haddad, Athena P Kourtis

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Contraception, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Anuli N NwaohiriDivision of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Jennifer H TangUniversity of North Carolina Project, Lilongwe, Malawi.
Frank StanczykDepartment of Obstetrics and Gynecology, University of Southern California Keck School of Medicine.
Lameck ChinulaUniversity of North Carolina Project, Lilongwe, Malawi.
Stacey HurstDivision of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Nicole L DavisDivision of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Gerald TeghaUniversity of North Carolina Project, Lilongwe, Malawi.
Lisa HaddadEmory University, Department of Obstetrics & Gynecology, Atlanta, GA, USA.
Athena P KourtisDivision of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: apk3@cdc.gov.
Centers for Disease Control and Prevention · USEmory University · USUniversity of Southern California · US

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Carlos del Rio · 2002 to 2026
$74.0M
Impact of progestin contraception on risk of HIV acquisition and transmissionK23HD078153 · NICHD · EMORY UNIVERSITY · PI HADDAD, LISA BLAKE · 2014 to 2018
$704k
Evaluation of the immunologic and genital tract changes among Malawian women K01TW009657 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI TANG, JENNIFER · 2013 to 2016
$565k
ACL HHS U48DP001944FIC NIH HHS K01 TW009657NIAID NIH HHS P30 AI050409NIAID NIH HHS P30 AI050410NICHD NIH HHS K23 HD078153
6 · The paper itself

Abstract

objectiveThe objective was to assess the extent of concordance between self-reported contraceptive use and the presence of contraceptive progestins in serum. STUDY

designWe evaluated self-reported contraceptive use by using radioimmunoassay to examine baseline serum levels of medroxyprogesterone acetate (MPA) and levonorgestrel (LNG) among 97 Malawian women enrolling in a contraceptive trial.

resultsTwelve percent (12/97) of study participants who reported no hormonal contraceptive use in the previous 6months had either MPA or LNG detected in their serum.

conclusionsThe observed discordance between self-report and detection of exogenous hormones in serum indicates that caution is warranted when drawing conclusions based on self-reported contraceptive use.

Indexed as

Self ReportAdultContraception BehaviorContraceptive Agents, FemaleFemaleHumansLevonorgestrelMalawiMedroxyprogesterone AcetateRadioimmunoassayTruth DisclosureContraceptive Agents, FemaleLevonorgestrelMedroxyprogesterone AcetateContraceptive useDiscordanceLevonorgestrel (LNG)Medroxyprogesterone acetate (MPA)Misreporting

Identifiers

PMID29246819
PMCPMC5840008
OpenAlexW2771163822

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.