Evidence map›Paper›PMID 29246585›Full record

SynthesisRadiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology2018

Exposure of the lungs in breast cancer radiotherapy: A systematic review of lung doses published 2010-2015.

Marianne C Aznar, Frances K Duane, Sarah C Darby, Zhe Wang, Carolyn W Taylor

Abstract readSystematic Review
In one paragraph

Synthesis in Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marianne C AznarClinical Trial Service Unit, Nuffield Department of Population Health, University of Oxford, UK; Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Denmark. Electronic address: marianne.aznar@ndph.ox.ac.uk.
Frances K DuaneMedical Research Council Population Health Research Unit, Nuffield Department of Population Health, University of Oxford, UK.
Sarah C DarbyClinical Trial Service Unit, Nuffield Department of Population Health, University of Oxford, UK.
Zhe WangMedical Research Council Population Health Research Unit, Nuffield Department of Population Health, University of Oxford, UK.
Carolyn W TaylorClinical Trial Service Unit, Nuffield Department of Population Health, University of Oxford, UK.

Funding

British Heart FoundationCancer Research UK 21133Cancer Research UK C8225/A21133Medical Research Council MC_U137686850Medical Research Council MC_U137686858
6 · The paper itself

Abstract

background and purposeWe report a systematic review of lung radiation doses from breast cancer radiotherapy. METHODS AND MATERIALS: Studies describing breast cancer radiotherapy regimens published during 2010-2015 and reporting lung dose were included. Doses were compared between different countries, anatomical regions irradiated, techniques and use of breathing adaptation.

results471 regimens from 32 countries were identified. The average mean ipsilateral lung dose (MLD

conclusionsLung doses from breast cancer radiotherapy varied substantially worldwide, even between studies describing similar regimens. Lymph node inclusion and IMRT use increased exposure, while breathing adaptation and prone/lateral decubitus positioning reduced it.

Indexed as

Breast NeoplasmsFemaleHumansLungRadiotherapy DosageRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedBreast cancerBreathing adaptationImrtLung dose

Identifiers

PMID29246585
PMCPMC5807032

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.